Past studies have shown that non-dipper hypertensive patients have more frequent subclinical left ventricular (LV) systolic dysfunction compared to dippers. Many different parameters have been examined to predict subclinical LV dysfunction. The role of osteoprotegerin (OPG) in the pathogenesis of heart failure and LV systolic dysfunction through different mechanisms had well described. In the present study, we hypothesized that increased OPG levels could predict subclinical LV systolic dysfunction in non-dipper hypertensive patients.

中文翻译：

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骨保护素与非杓型高血压患者的亚临床左心室收缩功能障碍相关：一项 2D 斑点追踪超声心动图研究。

过去的研究表明，与杓型高血压患者相比，非杓型高血压患者更容易出现亚临床左心室（LV）收缩功能障碍。已经检查了许多不同的参数来预测亚临床左心室功能障碍。骨保护素（OPG）通过不同机制在心力衰竭和左心室收缩功能障碍的发病机制中的作用已得到很好的描述。在本研究中，我们假设 OPG 水平升高可以预测非杓型高血压患者的亚临床左室收缩功能障碍。