As a significant cause of global morbidity and mortality, Clostridioides difficile infections (CDIs) are listed by the Centres for Disease Control and prevention as one of the top 5 urgent threats in the USA. CDI occurs from gut microbiome dysbiosis, typically through antibiotic-mediated disruption; however, antibiotics are the treatment of choice, which can result in recurrent infections. Here, we highlight new treatments available and provide a perspective on different classes of future treatments.

中文翻译：

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艰难梭菌感染；新的治疗方法和未来的前景。

作为全球发病率和死亡率的一个重要原因，艰难梭菌感染 (CDI) 被美国疾病控制和预防中心列为美国 5 大紧急威胁之一。CDI 是由肠道微生物群失调引起的，通常是通过抗生素介导的破坏；然而，抗生素是首选治疗方法，但可能导致反复感染。在这里，我们重点介绍可用的新治疗方法，并提供对未来不同类别治疗方法的看法。