Background. Hypertrophic cardiomyopathy (HCM) has different complications such as cardiac arrhythmia and sudden cardiac death (SCD). Insertion of an implantable cardioverter defibrillator (ICD) is recommended for HCM patients who are at high risk of SCD and malignant arrhythmias, despite having their own potential complications. Hypothesis. We aimed to investigate the prevalence of different complications of ICD insertion and the impact of the potential influential baseline characteristics in a one-year follow-up period. Methods. This was a retrospective study with a total of 71 HCM patients with ICD insertion. We evaluated the prevalence of different complications of ICD implantation and the impact of baseline characteristics on the occurrence of ICD complications using multivariate regression analysis in three 4-month periods. Results. In a one-year follow-up, 13 patients (18.3%) experienced at least one of the complications including pneumothorax, lead failure, ICD infection, inappropriate shocks, perforation, and upper limb deep vein thrombosis (DVT) with no mortality. Inappropriate shocks were reported as the most common (11.3%) complication during this period, with a gradual increase in the second (4.2%) and third (5.6%) follow-up sessions. Among all of the baseline characteristics that were investigated in this study, a positive history of hypertension was the only risk factor with significant impact on the occurrence of complications ( = 0.01). Conclusion. We demonstrated the occurrence of complications during a one-year follow-up as 18.3% in HCM patients with ICD insertion. A positive history of hypertension was the only baseline characteristic affecting the occurrence of complications, and inappropriate shocks were the most common complication.

中文翻译：

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肥厚型心肌病患者植入式心脏复律除颤器的并发症及其潜在危险因素

背景。肥厚型心肌病（HCM）具有不同的并发症，例如心律失常和心源性猝死（SCD）。尽管存在潜在的并发症，但对于 SCD 和恶性心律失常高风险的 HCM 患者，仍建议插入植入式心律转复除颤器 (ICD)。假设。我们的目的是调查植入 ICD 的不同并发症的发生率以及一年随访期内潜在影响基线特征的影响。方法。这是一项回顾性研究，共有 71 名植入 ICD 的 HCM 患者。我们使用多元回归分析评估了 ICD 植入不同并发症的发生率以及基线特征对 ICD 并发症发生的影响，为期三个 4 个月。结果。在一年的随访中，13 名患者 (18.3%) 经历了至少一种并发症，包括气胸、导线故障、ICD 感染、不适当的电击、穿孔和上肢深静脉血栓 (DVT)，但没有死亡。据报告，不适当的电击是这一时期最常见的并发症（11.3%），在第二次（4.2%）和第三次（5.6%）随访中逐渐增加。在本研究调查的所有基线特征中，高血压阳性病史是唯一对并发症发生具有显着影响的危险因素（ = 0.01）。结论。我们证明，在植入 ICD 的 HCM 患者中，一年随访期间并发症的发生率为 18.3%。高血压病史是影响并发症发生的唯一基线特征，不适当的电击是最常见的并发症。