INTRODUCTION Long-term complication rates in standard transvenous pacemakers are reported around 4-12% with a higher incidence in the elderly population. We report our experience in octogenarians undergoing leadless pacemaker implantation in two large-volume centers in Switzerland. METHODS Consecutive patients undergoing leadless pacemaker implantation at two Swiss large volume centers (University Hospital Zurich, Zurich and Cardiocentro Ticino Institute, Lugano) between October 2015 and March 2020 were included in this retrospective analysis. Demographic information, clinical data, and procedural characteristics were recorded at the day of implantation and during follow-up. RESULTS Two hundred and twenty patients (mean age 80.6 ± 7.7 years, male 66%) were included. The main indication for pacemaker implantation was slow ventricular rate atrial fibrillation (111 of 220 patients, 50.4%). Out of the 220 patients, 124 (56.3%) were ≥80 years. Overall successful implantation rate was 98.6%. In the octogenarian population, the median procedure time (45 ± 20.2 min vs. 40 ± 19.6 min, p = 0.03) and radiation duration (6.1 ± 8.2 min vs. 5.0 ± 7.2 min, p = 0.03) were longer compared to patients <80 years. Major complications (2.7%, n = 6) and device measurements during follow-up were similar between patients ≥80 and <80 years. CONCLUSION Implantation of a leadless pacemaker device in octogenarians is safe and effective with a similarly low complication rate compared to non-octogenarians.

中文翻译：

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八旬老人植入无引线起搏器的有效性和安全性。

引言 据报道，标准经静脉起搏器的长期并发症发生率约为 4-12%，其中老年人群的发生率更高。我们报告了在瑞士两个大型中心对八旬老人进行无引线起搏器植入的经验。方法 本回顾性分析纳入了 2015 年 10 月至 2020 年 3 月期间在两个瑞士大型中心（苏黎世苏黎世大学医院和卢加诺提契诺心脏研究所）连续接受无引线起搏器植入的患者。在植入当天和随访期间记录人口统计信息、临床数据和程序特征。结果 纳入 220 名患者（平均年龄 80.6 ± 7.7 岁，男性 66%）。起搏器植入的主要适应症是慢心室率房颤（220 名患者中的 111 名，占 50.4%）。在 220 名患者中，124 名（56.3%）年龄≥80 岁。总体植入成功率为98.6%。在八十多岁人群中，中位手术时间（45 ± 20.2 分钟 vs. 40 ± 19.6 分钟，p = 0.03）和辐射持续时间（6.1 ± 8.2 分钟 vs. 5.0 ± 7.2 分钟，p = 0.03）比<<的患者更长。 80 年。≥80 岁和 <80 岁患者的主要并发症（2.7%，n = 6）和随访期间的设备测量结果相似。结论 与非八旬老人相比，八旬老人植入无引线起搏器装置是安全有效的，并发症发生率同样较低。