We explored perspectives of patients with metastatic non-small cell lung cancer (mNSCLC) on symptom screening and population-level patient-reported outcome (PRO) data regarding common symptom trajectories in the year after diagnosis. A qualitative study of patients with mNSCLC was conducted at a Canadian tertiary cancer centre. English-speaking patients diagnosed ≥ 6 months prior to study invitation were recruited, and semi-structured one-on-one interviews were conducted. Patient and treatment characteristics were obtained via chart review. Anonymized interview transcripts underwent deductive-inductive coding and thematic content analysis. Among ten participants (5 (50%) females; median (range) age, 68 (56–77) years; median (range) time since diagnosis, 28.5 (6–72) months; 6 (60%) with smoking histories), six themes were identified in total. Two themes were identified regarding symptom screening: (1) screening is useful for symptom self-monitoring and disclosure to the healthcare team, (2) screening of additional quality-of-life (QOL) domains (smoking-related stigma, sexual dysfunction, and financial toxicity) is desired. Four themes were identified regarding population-level symptom trajectory PRO data: (1) data provide reassurance and motivation to engage in symptom self-management, (2) data should be disclosed after an oncologic treatment plan is developed, (3) data should be communicated via in-person discussion with accompanying patient-education resources, and (4) communication of data should include reassurance about symptom stabilization, acknowledgement of variability in patient experience, and strategies for symptom self-management. The themes and recommendations derived from the patient experience with mNSCLC provide guidance for enhanced symptom screening and utilization of population-level symptom trajectory data for patient education.

我们探讨了转移性非小细胞肺癌 (mNSCLC) 患者对症状筛查和诊断后一年常见症状轨迹的人群水平患者报告结果 (PRO) 数据的看法。加拿大三级癌症中心对 mNSCLC 患者进行了一项定性研究。招募了在研究邀请前 ≥ 6 个月确诊的英语患者，并进行了半结构化的一对一访谈。通过图表审查获得患者和治疗特征。匿名访谈记录经过演绎归纳编码和主题内容分析。10 名参与者（5 名（50%）女性；中位（范围）年龄，68（56-77）岁；自诊断后中位（范围）时间，28.5（6-72）个月；6 名（60%）有吸烟史） ，总共确定了六个主题。关于症状筛查，确定了两个主题：(1) 筛查有助于症状自我监测和向医疗团队披露，(2) 筛查其他生活质量 (QOL) 领域（与吸烟相关的耻辱、性功能障碍、和经济毒性）是所希望的。关于人群水平症状轨迹 PRO 数据确定了四个主题：(1) 数据提供了进行症状自我管理的保证和动力，(2) 应在制定肿瘤治疗计划后披露数据，(3) 数据应通过与患者教育资源的面对面讨论进行沟通，(4) 数据交流应包括保证症状稳定、承认患者经历的可变性以及症状自我管理策略。来自 mNSCLC 患者经历的主题和建议为加强症状筛查和利用人群水平症状轨迹数据进行患者教育提供了指导。