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Diagnosis and management of primary hyperaldosteronism in patients with hypertension: a practical approach endorsed by the British and Irish Hypertension Society
Journal of Human Hypertension ( IF 2.7 ) Pub Date : 2023-11-14 , DOI: 10.1038/s41371-023-00875-1
Luca Faconti 1 , Spoorthy Kulkarni 2 , Christian Delles 3 , Vikas Kapil 4, 5 , Philip Lewis 6 , Mark Glover 7 , Thomas M MacDonald 8 , Ian B Wilkinson 9
Affiliation  

Alongside the lack of homogeneity among international guidelines and consensus documents on primary hyperaldosteronism, the National UK guidelines on hypertension do not provide extensive recommendations regarding the diagnosis and management of this condition. Local guidelines vary from area to area, and this is reflected in the current clinical practice in the UK. In an attempt to provide support to the clinicians involved in the screening of subjects with hypertension and clinical management of suspected cases of primary hyperaldosteronism the following document has been prepared on the behalf of the BIHS Guidelines and Information Service Standing Committee. Through remote video conferences, the authors of this document reviewed an initial draft which was then circulated among the BIHS Executive members for feedback. A survey among members of the BIHS was carried out in 2022 to assess screening strategies and clinical management of primary hyperaldosteronism in the different regions of the UK. Feedback and results of the survey were then discussed and incorporated in the final document which was approved by the panel after consensus was achieved considering critical review of existing literature and expert opinions. Grading of recommendations was not performed in light of the limited available data from properly designed randomized controlled trials.



中文翻译:

高血压患者原发性醛固酮增多症的诊​​断和治疗:英国和爱尔兰高血压协会认可的实用方法

除了原发性醛固酮增多症的国际指南和共识文件缺乏一致性之外,英国国家高血压指南也没有提供有关这种疾病的诊断和治疗的广泛建议。当地指南因地区而异,这反映在英国当前的临床实践中。为了向参与高血压受试者筛查和原发性醛固酮增多症疑似病例临床管理的临床医生提供支持,代表 BIHS 指南和信息服务常务委员会编写了以下文件。通过远程视频会议,本文件的作者审查了初稿,然后在 BIHS 执行成员之间分发以征求反馈。2022 年对 BIHS 成员进行了一项调查,以评估英国不同地区原发性醛固酮增多症的筛查策略和临床管理。然后对调查的反馈和结果进行讨论,并将其纳入最终文件中,在考虑对现有文献和专家意见进行严格审查后达成共识后,该文件由专家组批准。鉴于正确设计的随机对照试验的可用数据有限,未对建议进行分级。

更新日期:2023-11-14
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