Introduction: Prescription of second-generation antipsychotics (SGAs) in youths is rapidly increasing globally, despite the potential for significant adverse effects and long-term health consequences. A known adverse reaction resulting from SGAs is metabolic syndrome (MS). Youths exposed to antipsychotics are at higher risk than adults for adverse drug reactions, including adverse events such as MS (with weight gain as the most significant adverse outcome) and other long-term endocrinological abnormalities. This study aimed to explore the experiences of young patients on factors impacting barriers to metabolic monitoring of SGAs and the strategies to address those barriers thereby providing further guidance on policy and service delivery. Methods: Semi-structured interviews were conducted with patients (youths who were prescribed SGAs) who attended Child and Youth Mental Health Services. The interviews focused on barriers to monitoring and strategies to enhance rates of monitoring that could be customized across study sites. Results: Young patients revealed that none of them had any concerns or objections to receiving anthropometric metabolic measurements. However, they seemed concerned to undergo blood tests as part of the metabolic monitoring process. Specifically, youths cited their fear of the needles as barrier to undergo the required blood tests. Youths have also reported that their dislike to healthy foods and exercise being the most common challenge they face while trying to engage in a healthy lifestyle to manage the SGAs resulted weight gain. Conclusion: Prescribers are recommended to actively engage young patients about the expected SGAs-induced adverse effects, the importance of conducting metabolic monitoring, and how to prevent and minimize the expected adverse effects from the start of initiating SGAs. This could be a vital step toward a successful treatment as the insight of youths into the details of the chosen treatment can play a significant role into treatment adherence and recovery.

中文翻译：

---

了解青少年在使用第二代抗精神病药物时接受代谢监测的观点：挑战、见解和影响。

简介：尽管第二代抗精神病药 (SGA) 可能会产生严重的副作用和长期的健康后果，但全球青少年的第二代抗精神病药 (SGA) 处方正在迅速增加。SGA 引起的一种已知不良反应是代谢综合征 (MS)。接触抗精神病药物的青少年比成年人面临更高的药物不良反应风险，包括 MS 等不良事件（体重增加是最显着的不良后果）和其他长期内分泌异常。本研究旨在探讨年轻患者对 SGA 代谢监测障碍影响因素的经验以及解决这些障碍的策略，从而为政策和服务提供提供进一步指导。方法：对参加儿童和青少年心理健康服务的患者（服用 SGA 的青少年）进行半结构化访谈。访谈的重点是监测障碍和提高监测率的策略，这些策略可以在各个研究中心进行定制。结果：年轻患者透露，他们中没有人对接受人体代谢测量有任何担忧或反对。然而，他们似乎担心接受血液检查作为代谢监测过程的一部分。具体来说，年轻人表示对针头的恐惧是接受所需血液检查的障碍。青少年还报告说，他们对健康食品和运动的不喜欢是他们在尝试采用健康的生活方式来管理 SGA 时面临的最常见挑战，导致体重增加。结论：建议处方者积极让年轻患者了解 SGA 引起的预期不良反应、进行代谢监测的重要性，以及如何从开始 SGA 开始就预防和尽量减少预期不良反应。这可能是迈向成功治疗的重要一步，因为青少年对所选治疗细节的深入了解可以对治疗依从性和康复发挥重要作用。