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Is intravenous valproate more efficacious than oral valproate for inpatients with bipolar I disorder with a manic or depressive episode and concomitant symptoms of opposite polarity?
Bipolar Disorders ( IF 5.4 ) Pub Date : 2023-11-13 , DOI: 10.1111/bdi.13388
Alessandro Cuomo 1 , Giovanni Barillà 1 , Matteo Cattolico 1 , Pietro Carmellini 1 , Alessandro Spiti 1 , Andrea Pozza 2 , Andrea Fagiolini 1
Affiliation  

Valproic acid (VPA) is a commonly prescribed mood stabilizer, available in both oral (OS) and intravenous (IV) formulations. However, few studies have compared their safety and efficacy. This retrospective study aimed to investigate the safety and efficacy of and IV-VPA in patients with Bipolar Disorder.

中文翻译:

对于患有躁狂或抑郁发作并伴有相反极性症状的 I 型双相情感障碍住院患者,静脉注射丙戊酸是否比口服丙戊酸更有效?

丙戊酸 (VPA) 是一种常用的情绪稳定剂,有口服 (OS) 和静脉注射 (IV) 两种制剂。然而,很少有研究比较它们的安全性和有效性。这项回顾性研究旨在调查 IV-VPA 对双相情感障碍患者的安全性和有效性。
更新日期:2023-11-14
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