Animal parasitic diseases not only have an economic impact, but also have serious social and public health impacts. Although antiparasitic drugs can treat these diseases, it seems difficult for users to comprehensively utilize the information, due to incomplete and difficult data collection. Thus, there is an urgent need to establish a comprehensive database, that includes parasitic diseases and related drugs. In this paper, we develop a knowledge database dedicated to collecting and analyzing animal parasitic diseases and related drugs, named Animal Parasitic Diseases and Drugs Database (APDDD). The current version of APDDD includes animal parasitic disease data of 8 major parasite classifications that cause common parasitic diseases and 96 subclass samples mined from many literature and authoritative books, as well as 182 antiparasitic drugs. Furthermore, we utilized APDDD data to add a knowledge graph representing the relationships between parasitic diseases, drugs, and the targeted gene of drugs acting on parasites. We hope that APDDD will become a good database for animal parasitic diseases and antiparasitic drugs research and that users can gain a more intuitive understanding of the relationships between parasitic diseases, drugs, and targeted genes through the knowledge graph.

动物寄生虫病不仅产生经济影响，而且还产生严重的社会和公共卫生影响。尽管抗寄生虫药物可以治疗这些疾病，但由于数据收集不完整且困难，用户似乎很难综合利用这些信息。因此，迫切需要建立一个包括寄生虫病和相关药物的综合数据库。在本文中，我们开发了一个专门收集和分析动物寄生虫病及相关药物的知识数据库，命名为动物寄生虫病和药物数据库（APDDD）。当前版本的APDDD包括引起常见寄生虫病的8个主要寄生虫分类的动物寄生虫病数据和从众多文献和权威书籍中挖掘的96个亚类样本，以及182种抗寄生虫药物。此外，我们利用APDDD数据添加了一个知识图谱，表示寄生虫病、药物以及作用于寄生虫的药物的靶基因之间的关系。我们希望APDDD能够成为动物寄生虫病和抗寄生虫药物研究的良好数据库，让用户能够通过知识图谱更直观地了解寄生虫病、药物和靶基因之间的关系。