Front cover: Mouse sperm are immature immediately after production in the testis. Lumicrine factors (NELL2 and NICOL) secreted by the testis stimulate the differentiation of epididymal initial segment epithelial cells, and these epithelial cells are responsible for processing the ADAM3 protein on the sperm surface, resulting in sperm maturation. For details, see the review article in this issue (Kiyozumi (2023) Genes Cells 28: 757-763, DOI: 10.1111/gtc.13066). The boys with long hair in this drawing also have their hair cut at the barbershops at the approach to a bridge and go out into the world, crossing the bridge as mature men. Designed by TRAIS Co., Ltd. (Kobe, Japan).

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发行信息

封面：小鼠精子在睾丸中产生后立即不成熟。睾丸分泌的Lumicrine因子（NELL2和NICOL）刺激附睾初段上皮细胞的分化，这些上皮细胞负责加工精子表面的ADAM3蛋白，导致精子成熟。详细内容请参见本期综述文章（Kiyozumi (2023) Genes Cells 28: 757-763, DOI: 10.1111/gtc.13066）。这幅画中的长发男孩也是在桥边的理发店理发，走出去，以成熟男人的身份跨过桥。由 TRAIS Co., Ltd.（日本神户）设计。