In this study, a selective SBA-15 /Fe₃O₄/Polyaniline /Chitosan nanocomposite was successfully electrodeposited on Screen- Printed Carbon Electrode (SPCE) and used for L-Tyrosine (Tyr) detection.

Biological diagnostic probes such as artificial receptors are one of the important diagnostic layers for the identification of vital biomolecules, including essential amino acids like Tyr. A new electrochemical sensing platform based on differential pulse voltammetry was prepared for selective determination of Tyr in milk samples.

SBA-15 nanoparticles were synthesized from corn leaves as a source of silica. These high-absorbance nanoparticles have been used for surface modification of SPCE. The morphology and electrochemical performance of the modified electrode were characterized by X-ray diffraction, scanning electron microscopy (SEM), transition electron microscopy (TEM), Furrier transform infrared spectroscopy (FTIR), Brunauer-Emmett–Teller techniques, electrochemical impedance spectroscopy (EIS), and cyclic voltammetry(CV).

As a novel modified electrode, the catalytic activity of the modified SPCE towards electro-oxidation of Tyr was measured by differential pulse voltammetry (DPV). The experimental conditions, including the adsorption time, scan rates, the ratio of SBA-15, pH value, and applied potential, are investigated in detail.

Electrochemical sensor based on SBA-15 (SPCE/SBA-15/Fe₃O₄/Polyaniline /Chitosan) Compared with SPCE/Fe₃O₄/Polyaniline/Chitosan shows good sensitivity, repeatability, reproducibility, low detection limit and high selectivity.

In addition, a linear correlation between oxidation peak current and concentration of Tyr in the ranges 0.1–250 μM with a detection limit of 0.05 μM (S/N = 3) was obtained. Eventually, the suggested sensor was used for quantification of Tyr in real samples, by adding standard solutions to the milk samples.

在本研究中，选择性SBA-15/Fe ₃ O ₄ /聚苯胺/壳聚糖纳米复合材料成功电沉积在丝网印刷碳电极(SPCE)上并用于L-酪氨酸(Tyr)检测。

人工受体等生物诊断探针是识别重要生物分子（包括酪氨酸等必需氨基酸）的重要诊断层之一。制备了一种基于微分脉冲伏安法的新型电化学传感平台，用于选择性测定牛奶样品中的酪氨酸。

SBA-15 纳米粒子是用玉米叶作为二氧化硅来源合成的。这些高吸光度纳米颗粒已用于 SPCE 的表面修饰。通过 X 射线衍射、扫描电子显微镜 (SEM)、过渡电子显微镜 (TEM)、傅里叶变换红外光谱 (FTIR)、Brunauer-Emmett-Teller 技术、电化学阻抗谱等手段对修饰电极的形貌和电化学性能进行了表征。 EIS）和循环伏安法（CV）。

作为一种新型修饰电极，通过微分脉冲伏安法（DPV）测量了修饰SPCE对Tyr电氧化的催化活性。详细研究了实验条件，包括吸附时间、扫描速率、SBA-15的比例、pH值和外加电位。

基于SBA-15(SPCE/SBA-15/Fe ₃ O _{4 /聚苯胺/壳聚糖)的电化学传感器与SPCE/Fe 3} O ₄ /聚苯胺/壳聚糖相比表现出良好的灵敏度、重复性、重现性、低检测限和高选择性。

此外，氧化峰电流与 Tyr 浓度在 0.1-250 μM 范围内呈线性相关，检测限为 0.05 μM (S/N = 3)。最终，通过向牛奶样品中添加标准溶液，建议的传感器被用于实际样品中 Tyr 的定量。