Pharmacokinetic evaluation of oxaliplatin combined with S-1 (SOX) chemotherapy in a rat model of colorectal cancer with acute kidney injury: predictive renal biomarkers for dose optimisation,Xenobiotica

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Pharmacokinetic evaluation of oxaliplatin combined with S-1 (SOX) chemotherapy in a rat model of colorectal cancer with acute kidney injury: predictive renal biomarkers for dose optimisation
Xenobiotica ( IF 1.8 ) Pub Date : 2023-12-19 , DOI: 10.1080/00498254.2023.2283736
Takumi Tanaka ₁ , Shinji Kobuchi ₁ , Yukako Ito ₁ , Toshiyuki Sakaeda ₁

Affiliation

Dose adjustment based on renal function is essential in S-1, which contains the 5‑fluorouracil prodrug tegafur, and platinum-based agent oxaliplatin (SOX) combination chemotherapy for colorectal c...

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