The study was carried out to investigate the effect of the artery with different pulse values and stenosis rates on the pressure drop, the peristaltic pump outlet pressure, fractional flow reserve (FFR) and most importantly the amount of power consumed by the peristaltic pump. For this purpose, images taken from the clinical environment were produced as models (10 mm inlet diameter) with 0% and 70% percent areal stenosis rates (PSR) on a three-dimensional (3D) printer. In the experimental system, pure water was used as the fluid at 54, 84, 114, 132, and 168 bpm pulse values. In addition, computational fluid dynamics (CFD) analyzes of the test region were performed using experimental boundary conditions with the help of ANSYS-Fluent software. The findings showed that as PSR increases in the arteries, the pressure drop in the stenosis region increases and this amount increases dramatically with increasing effort. An increase of approximately 40% was observed in the pump outlet pressure value from 54 bpm to 168 bpm in the PSR 0% model and 51% increase in the PSR 70% model. It has been observed that the pump does more work to overcome the increased pressure difference due to increased pulse rate and PSR. With the effect of contraction, the power consumption of the pump increased from 9.2% for 54 bpm to 13.8% for 168 bpm. In both models, the Wall Shear Stress (WSS) increased significantly. WSS increased abruptly in the stenosis and arcuate regions, while sudden decreases were observed in the flow separation region.

中文翻译：

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对临床环境下的狭窄冠状动脉进行实验和数值研究，并根据血流动力学进行建模

该研究旨在研究不同脉搏值和狭窄率的动脉对压降、蠕动泵出口压力、流量储备分数（FFR）以及最重要的是蠕动泵消耗的功率的影响。为此，在三维 (3D) 打印机上将从临床环境拍摄的图像制作为模型（入口直径为 10 毫米），面积狭窄率 (PSR) 为 0% 和 70%。在实验系统中，使用纯水作为流体，脉冲值为 54、84、114、132 和 168 bpm。此外，在 ANSYS-Fluent 软件的帮助下，使用实验边界条件对测试区域进行了计算流体动力学 (CFD) 分析。研究结果表明，随着动脉 PSR 的增加，狭窄区域的压降也会增加，并且随着努力的增加，压力降会急剧增加。在 PSR 0% 模型中观察到泵出口压力值从 54 bpm 增加到 168 bpm 增加了约 40%，在 PSR 70% 模型中增加了 51%。据观察，泵会做更多的功来克服由于脉冲速率和 PSR 增加而导致的压差增加。由于收缩的影响，泵的功耗从 54 bpm 时的 9.2% 增加到 168 bpm 时的 13.8%。在这两个模型中，壁剪应力 (WSS) 显着增加。WSS 在狭窄和弓形区域突然增加，而在血流分离区域观察到突然减少。