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Effect of Repeated Exposure to Sevoflurane on Electroencephalographic Alpha Oscillation in Pediatric Patients Undergoing Radiation Therapy: A Prospective Observational Study.
Journal of Neurosurgical Anesthesiology ( IF 3.7 ) Pub Date : 2023-11-13 , DOI: 10.1097/ana.0000000000000938
Samuel Madariaga 1, 2 , Christ Devia 1, 2 , Antonello Penna 3, 4 , José I Egaña 1, 4 , Vanessa Lucero 5 , Soledad Ramírez 5 , Felipe Maldonado 4 , Macarena Ganga 5 , Nicolás Valls 5 , Nicolás Villablanca 5 , Tomás Stamm 5 , Patrick L Purdon 6 , Rodrigo Gutiérrez 3, 4, 6
Affiliation  

Pharmacological tolerance is defined as a decrease in the effect of a drug over time, or the need to increase the dose to achieve the same effect. It has not been established whether repeated exposure to sevoflurane induces tolerance in children.

中文翻译:

重复暴露于七氟醚对接受放射治疗的儿科患者脑电图 Alpha 振荡的影响:一项前瞻性观察研究。

药理学耐受性定义为药物效果随着时间的推移而降低,或者需要增加剂量才能达到相同的效果。目前尚未确定反复接触七氟醚是否会引起儿童耐受。
更新日期:2023-11-13
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