A novel N-heterocycles substituted oseltamivir derivatives as potent inhibitors of influenza virus neuraminidase: discovery, synthesis and biological evaluation,Journal of Enzyme inhibition and Medicinal Chemistry

当前位置： X-MOL 学术 › J. Enzyme Inhib. Med. Chem. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

A novel N-heterocycles substituted oseltamivir derivatives as potent inhibitors of influenza virus neuraminidase: discovery, synthesis and biological evaluation
Journal of Enzyme inhibition and Medicinal Chemistry ( IF 5.6 ) Pub Date : 2023-11-13 , DOI: 10.1080/14756366.2023.2277135
Jiwei Zhang ₁ , Chuanfeng Liu _{1,

2} , Ruifang Jia ₁ , Xujie Zhang ₁ , Jian Zhang ₃ , Chiara Bertagnin ₄ , Anna Bonomini ₄ , Laura Guizzo ₄ , Yuanmin Jiang ₁ , Huinan Jia ₁ , Shuzhen Jia ₁ , Xiuli Ma ₅ , Arianna Loregian ₄ , Bing Huang ₅ , Peng Zhan _{1,

6} , Xinyong Liu _{1,

6}

Affiliation

Our previous studies have shown that the introduction of structurally diverse benzyl side chains at the C5-NH2 position of oseltamivir to occupy 150-cavity contributes to the binding affinity with ...

中文翻译：