Methotrexate, an anti-inflammatory drug, inhibits Hepatitis E viral replication,Journal of Enzyme inhibition and Medicinal Chemistry

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Methotrexate, an anti-inflammatory drug, inhibits Hepatitis E viral replication
Journal of Enzyme inhibition and Medicinal Chemistry ( IF 5.6 ) Pub Date : 2023-11-17 , DOI: 10.1080/14756366.2023.2280500
Akash Kumar ₁ , Preeti Hooda ₁ , Anindita Puri ₁ , Radhika Khatter ₁ , Mohammed S Al-Dosari ₂ , Neha Sinha ₃ , Mohammad K Parvez ₂ , Deepak Sehgal ₁

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Hepatitis E Virus (HEV) is a positively oriented RNA virus having a 7.2 kb genome. HEV consists of three open reading frames (ORF1-3). Of these, ORF1 codes for the enzymes Methyltransferase (Mtase)...

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