BACKGROUND Toxoplasmosis is one of the most common parasitic infections worldwide with varying prevalence between human populations. These variations are mainly associated with human exposure to risk factors. In this article, the seroprevalence of Toxoplasma gondii infection and the risk factors associated with infection in 1729 blood donors from São José do Rio Preto, São Paulo, Brazil were analysed. METHODS The serological tests for detecting immunoglobulin M (IgM) and immunoglobulin G (IgG) anti-T. gondii were used. The risk factors associated with the infection were identified through the application of an epidemiological questionnaire. RESULTS The prevalence of T. gondii infection was 48.0%. The following factors were identified in the final model after multiple logistic regression analysis: drinking raw milk (p=0.003; odds ratio [OR] 1.364 [confidence interval {CI} 1.1 to 1.7]), residing in a rural area (p<0.0001; OR 2.764 [CI 1.7 to 4.6]) and receiving a blood transfusion (p=0.015; OR 1.856 [CI 1.1 to 3.0]). CONCLUSIONS The data obtained in this study showed that the blood donor population is exposed to risk factors related to infection by T. gondii. These data allow the establishment of control programs to contribute to public health in northwestern São Paulo state.

中文翻译：

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巴西圣保罗州西北部地区献血者弓形虫感染的血清流行病学。

背景技术弓形虫病是世界范围内最常见的寄生虫感染之一，在人群之间的患病率不同。这些变化主要与人类接触危险因素有关。本文对来自巴西圣保罗普雷图河畔圣若泽的 1729 名献血者的弓形虫感染血清流行率以及与感染相关的危险因素进行了分析。方法血清学检测免疫球蛋白M（IgM）和免疫球蛋白G（IgG）抗T细胞。使用了弓形虫。通过流行病学调查问卷确定了与感染相关的危险因素。结果弓形虫感染率为48.0%。经过多重逻辑回归分析后，最终模型中确定了以下因素：饮用生奶（p=0.003；比值比 [OR] 1.364 [置信区间 {CI} 1.1 至 1.7]）、居住在农村地区（p<0.0001） ；OR 2.764 [CI 1.7 至 4.6]）并接受输血（p=0.015；OR 1.856 [CI 1.1 至 3.0]）。结论 本研究获得的数据表明，献血者群体暴露于与弓形虫感染相关的危险因素。这些数据有助于制定控制计划，为圣保罗州西北部的公共卫生做出贡献。