In this article, we have demonstrated a highly sensitive four-channel photonic crystal fiber (PCF) based surface plasmon resonance (SPR) biosensor which can detect four different analytes simultaneously. To ease practical implementation, four analyte sensing layers and plasmonic materials such as gold (Au) and gold (Au) with Tantalum Pentoxide (Ta2O5) are placed on the exterior of the four arms of the square shaped structure. The sensor’s structure consists of only nine circular air holes, making it simple and easy to fabricate using currently available technologies. Finite element method (FEM) based numerical analysis is used to evaluate the sensing performance of the proposed sensor. With optimum structure parameters, the sensor achieves maximum wavelength sensitivity of 11000, 25000, 11000 and 25000 nm/RIU for Channel-1, Channel-2, Channel-3, and Channel-4 respectively. It shows maximum amplitude sensitivity of 803.732, 709.171, 803.827, 709.146 RIU $^{-{1}}$ for Channel 1, 2, 3, and 4 respectively. It also shows maximum FOM of 232.55, 352.36, 231.57, 352.36 RIU $^{-{1}}$ in Ch-1, Ch-2, Ch-3 and Ch-4 respectively. Moreover, the proposed sensor shows a wide range of refractive index sensing capability from 1.30 to 1.41. Due to multi-analyte detection capability, large sensing range, and excellent sensitivity the proposed sensor unfolds unrivalled capacity of detecting chemicals, carcinogenic agents, biomolecules, and other analytes.

中文翻译：

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基于 PCF 的四通道 SPR 生物传感器，具有宽感应范围

在本文中，我们展示了一种基于表面等离子共振（SPR）的高灵敏度四通道光子晶体光纤（PCF）生物传感器，它可以同时检测四种不同的分析物。为了便于实际实施，四个分析物传感层和等离子体材料（例如金 (Au) 和金 (Au) 与五氧化二钽 (Ta2O5)）被放置在方形结构的四个臂的外部。该传感器的结构仅由九个圆形气孔组成，因此使用现有技术可以简单轻松地制造。基于有限元法（FEM）的数值分析用于评估所提出的传感器的传感性能。通过优化结构参数，传感器的通道1、通道2、通道3和通道4的最大波长灵敏度分别为11000、25000、11000和25000 nm/RIU。显示最大振幅灵敏度为 803.732、709.171、803.827、709.146 RIU $^{-{1}}$分别对应通道 1、2、3 和 4。它还显示最大 FOM 为 232.55、352.36、231.57、352.36 RIU $^{-{1}}$分别在 Ch-1、Ch-2、Ch-3 和 Ch-4 中。此外，所提出的传感器表现出从 1.30 到 1.41 的广泛折射率传感能力。由于具有多分析物检测能力、大传感范围和出色的灵敏度，该传感器在检测化学品、致癌剂、生物分子和其他分析物方面展现出无与伦比的能力。