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The worldwide need for amyloid diagnosis in animals
Journal of Biosciences ( IF 2.9 ) Pub Date : 2023-11-20 , DOI: 10.1007/s12038-023-00372-0
Akansha Garg , Ashwani Kumar Thakur

Deposition of amyloid in tissues and organs leads to amyloidosis, impacting the function of vital organs and often resulting in mortality. About 42 proteins in humans and 10 in animals are known to form amyloid deposits. Amyloid research in humans has gained considerable pace in recent years but not in the case of animals. Being an essential part of the ecosystem, animals contribute significantly to the world economy. Many retrospective studies have shown amyloidosis as a possible cause of animal death. Underdiagnosis of amyloidosis in animals may also increase the chance of zoonotic transmission. Hence, assessment of the prevalence of amyloidosis necessitates significant attention. An early diagnosis will improve the overall prognosis and decrease in the fatality of animals. This article strives to bring this issue to the attention of scientists, veterinarians, and primary caretakers of animals. This will help in the diagnosis and treatment of amyloidosis in animals.



中文翻译:

全世界对动物淀粉样蛋白诊断的需求

淀粉样蛋白在组织和器官中的沉积导致淀粉样变性,影响重要器官的功能并常常导致死亡。已知人类中约 42 种蛋白质和动物中约 10 种蛋白质可形成淀粉样蛋白沉积物。近年来,人类淀粉样蛋白研究取得了相当大的进展,但动物研究却进展缓慢。作为生态系统的重要组成部分,动物对世界经济做出了重大贡献。许多回顾性研究表明淀粉样变性可能是动物死亡的原因。动物淀粉样变性诊断不足也可能增加人畜共患传播的机会。因此,淀粉样变性患病率的评估需要引起高度重视。早期诊断将改善总体预后并减少动物死亡率。本文致力于引起科学家、兽医和动物主要看护者对这个问题的关注。这将有助于动物淀粉样变性的诊断和治疗。

更新日期:2023-11-22
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