AIM This study aimed to explore the factors contributing to mortality and its management among pediatric sepsis patients at a single center in Indonesia. METHOD We conducted a retrospective study of children admitted due to sepsis from January 2015 to December 2019 in an Indonesian tertiary hospital. RESULTS The mortality rate of pediatric sepsis in our study was 76.1% among 176 records with outcome identified. Mortality was significantly associated with septic shock at triage, number of organ failure, intensive care unit admission, inotropic use, septic shock and severe sepsis during hospitalization. Timing of antibiotic use did not affect mortality. Death within the first 24 h occurred in 41.8% of subjects, mostly due to septic shock. CONCLUSION This study illuminates the current state of pediatric sepsis management in our Indonesian hospital, revealing it as inadequate. Findings highlight the need for improved pre-hospital systems and sepsis recognition tools, and wider use of mechanical ventilators and advanced monitoring due to limited pediatric intensive care unit beds. Future research should focus on hospital-specific sepsis protocols to reduce pediatric sepsis mortality rates.

中文翻译：

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印度尼西亚一家三级医院的儿科败血症概况：一项为期 4 年的回顾性研究。

目的 本研究旨在探讨印度尼西亚单个中心的儿科脓毒症患者的死亡率及其管理的影响因素。方法 我们对 2015 年 1 月至 2019 年 12 月在印度尼西亚三级医院因败血症入院的儿童进行了回顾性研究。结果 在我们的研究中，在已确定结果的 176 份记录中，儿科败血症的死亡率为 76.1%。死亡率与分诊时的感染性休克、器官衰竭的数量、入住重症监护病房、正性肌力药物的使用、住院期间的感染性休克和严重脓毒症显着相关。抗生素使用时间不影响死亡率。41.8% 的受试者在最初 24 小时内死亡，主要是由于感染性休克。结论 这项研究阐明了我们印度尼西亚医院儿科脓毒症管理的现状，揭示了其不足。研究结果强调，由于儿科重症监护病房床位有限，需要改进院前系统和脓毒症识别工具，并更广泛地使用机械呼吸机和先进的监测。未来的研究应重点关注医院特定的脓毒症治疗方案，以降低儿童脓毒症死亡率。