Chemotherapy can cause many distressing side effects, potentially impacting treatment completion and quality of life in adolescent and young adult (AYA) patients with cancer. To identify ways to help mitigate chemotherapy-related symptoms, we sought to elicit barriers and facilitators to managing symptoms experienced by AYAs with cancer through interviews. Qualitative thematic analysis identified three main domains: (1) managing chemotherapy symptoms (e.g., medication, home remedies), (2) anticipating and mitigating symptoms (e.g., management of symptoms at home, anticipatory guidance), and (3) knowing when to seek care (e.g., unexpected and unusual symptoms). This study elucidated that AYAs can successfully manage symptoms at home when given the proper guidance and this could be a focus of future efforts to improve outcomes in this population. The Clinical Trial Registration number is NCT04594096.

中文翻译：

---

青少年和年轻癌症患者如何在家控制化疗相关症状？

化疗可能会导致许多令人痛苦的副作用，可能会影响青少年和年轻成人 (AYA) 癌症患者的治疗完成和生活质量。为了找到帮助减轻化疗相关症状的方法，我们试图通过访谈找出控制癌症 AYA 所经历的症状的障碍和促进因素。定性主题分析确定了三个主要领域：(1) 管理化疗症状（例如药物、家庭疗法），(2) 预测和缓解症状（例如在家管理症状、预期指导），以及 (3) 了解何时进行化疗寻求护理（例如，意外和不寻常的症状）。这项研究表明，在适当的指导下，AYA 可以成功地在家中控制症状，这可能是未来改善该人群治疗结果的努力的重点。临床试验注册号为NCT04594096。