Currently, clinical strategies for the treatment of wounds are limited, especially in terms of achieving rapid wound healing. In recent years, based on the technique of electrospinning (ES), cell electrospinning (C-ES) has been developed to better repair related tissues or organs (such as skin, fat and muscle) by encapsulating living cells in a microfiber or nanofiber environment and constructing 3D living fiber scaffolds. Therefore, C-ES has promising prospects for promoting wound healing. In this article, C-ES technology and its advantages, the differences between C-ES and traditional ES, the parameters suitable for maintaining cytoactivity, and material selection and design issues are summarized. In addition, we review the application of C-ES in the fields of biomaterials and cells. Finally, the limitations and improved methods of C-ES are discussed. In conclusion, the potential advantages, limitations and prospects of C-ES application in wound healing are presented.

中文翻译：

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细胞静电纺丝及其在伤口愈合中的应用：原理、技术和前景。

目前，治疗伤口的临床策略是有限的，特别是在实现伤口快速愈合方面。近年来，在静电纺丝（ES）技术的基础上，发展了细胞静电纺丝（C-ES），通过将活细胞封装在微纤维或纳米纤维环境中，更好地修复相关组织或器官（如皮肤、脂肪和肌肉）并构建3D活纤维支架。因此，C-ES在促进伤口愈合方面具有广阔的前景。本文对C-ES技术及其优点、C-ES与传统ES的区别、适合维持细胞活性的参数以及材料选择和设计问题进行了总结。此外，我们回顾了C-ES在生物材料和细胞领域的应用。最后讨论了C-ES的局限性和改进方法。总之，提出了 C-ES 在伤口愈合中应用的潜在优势、局限性和前景。