Glycosylation plays a crucial role in many aspects of cell biology, including cellular and organismal integrity, structure-and-function of many glycosylated molecules in the cell, signal transduction, development, cancer, and in a number of diseases. Besides, at the inter-organismal level of interaction, a variety of glycosylated molecules are involved in the host-microbiota recognition and initiation of downstream signalling cascades depending on the outcomes of the glycome-mediated ascertainment. The role of glycosylation in host-microbe interactions is better elaborated within the context of virulence and pathogenicity in bacterial infection processes but the symbiotic host-microbe relationships also involve substantive glycome-mediated interactions. The works in the latter field have been reviewed to a much lesser extent, and the main aim of this mini-review is to compensate for this deficiency and summarise the role of glycomics in host-microbe symbiotic interactions.

中文翻译：

---

糖组在共生宿主-微生物相互作用中的作用。

糖基化在细胞生物学的许多方面发挥着至关重要的作用，包括细胞和有机体的完整性、细胞中许多糖基化分子的结构和功能、信号转导、发育、癌症以及许多疾病。此外，在生物体间的相互作用水平上，多种糖基化分子参与宿主微生物群识别和下游信号级联的启动，具体取决于糖组介导的确定结果。糖基化在宿主-微生物相互作用中的作用在细菌感染过程中的毒力和致病性的背景下得到了更好的阐述，但共生的宿主-微生物关系也涉及实质性的糖组介导的相互作用。对后一个领域的工作的综述要少得多，这篇小综述的主要目的是弥补这一缺陷并总结糖组学在宿主-微生物共生相互作用中的作用。