Aim. To understand the degree of oncology patients’ awareness of drug clinical trials and oncology patients’ willingness to participate in drug clinical trials and the factors influencing them. Methods. The differences in the relevant variables of patients’ willingness to accept clinical trials were analyzed, and a descriptive analysis was done for the measurement data (mean and standard deviation). Pearson’s correlation coefficient analysis was used to examine the correlation between willingness and the demographic variables. Stepwise regression analysis was used to explore the influencing factors of patients’ willingness to accept clinical trials. Results. There were no statistical differences in age, gender, education level, marital status, place of residence, monthly income, medical payment method, and treatment time (). Patients’ willingness to accept drug clinical trials differed in their cognitive degree of clinical drug trials (). Patients’ willingness to accept drug clinical trials differed in their experience in clinical trials (). The correlation difference was statistically significant. The willingness to accept drug clinical trials was negatively correlated with treatment time (, ) and positively correlated with awareness of clinical trials and whether they had been subjects ( and 0.43, ). Multiple regression analysis showed that patients’ willingness was directly influenced by age, treatment time, and whether they had been subjects (, ). Conclusion. Age, treatment time, and whether they had been subjects were the direct influencing factors of patients’ willingness. This study pointed out that hospitals should do a good job in the publicity of clinical trials of new drugs, expand publicity channels, increase publicity efforts, improve the awareness of clinical trials of the masses, and promote the enthusiasm of the masses to participate in clinical trials of drugs.

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癌症患者临床试验的接受因素及心理调查

目的。了解肿瘤患者对药物临床试验的认知程度、肿瘤患者参与药物临床试验的意愿及其影响因素。方法。分析患者接受临床试验意愿相关变量的差异，并对测量数据（均值和标准差）进行描述性分析。皮尔逊相关系数分析用于检查意愿与人口变量之间的相关性。采用逐步回归分析探讨患者接受临床试验意愿的影响因素。结果。年龄、性别、受教育程度、婚姻状况、居住地、月收入、医疗支付方式、治疗时间等方面差异无统计学意义（）。患者接受药物临床试验的意愿因对药物临床试验的认知程度不同而存在差异（）。患者接受药物临床试验的意愿因临床试验经历不同而存在差异（）。相关性差异有统计学意义。接受药物临床试验的意愿与治疗时间呈负相关（, ）并且与临床试验的意识以及他们是否曾是受试者呈正相关（和 0.43，）。多元回归分析显示，患者的意愿直接受到年龄、治疗时间以及是否曾是受试者的影响（, ）。 结论。年龄、治疗时间、是否曾为受试者是患者意愿的直接影响因素。研究指出，医院应做好新药临床试验宣传工作，拓展宣传渠道，加大宣传力度，提高群众临床试验意识，促进群众参与临床试验的积极性。药物试验。