Recent years, multi-drug resistant bacteria (MDRs) and lung cancer cells are threatening to human worldwide due to failure of sufficient drugs. It was suggested that the new sources needed to discover new varieties of drugs, antibiotics and other format to eradicate these infections. As like, the medicinal plant of Morinda citrifolia (M. citrifolia) was used in this study to inhibit both the bacterial infection and cancer cells. First, the LC-MS measurement was evidently reported the available essential oils from medicinal plant of M. citrifolia. It has excellent anti-bacterial properties against P. mirabilis, E. coli, P. aeruginosa and S. aureus with 24, 22, 26 and 18 zone of inhibition respectively by agar well diffusion. Subsequently, the liquid interference assay was exhibited 97 %, 96 %, 94 % and 90 % inhibition at 1000 µg/mL concentration for all the tested pathogens. In addition, M. citrifolia EOs have excellent anti-bacterial activity, and it arrested the bacterial growth completely at 1000 µg/mL concentration for 24 h after compared with other time intervals. Subsequently, the intracellular membranes and more death cells with condensed chromosome like structure were effectively observed by confocal laser scanning electron microscope. Then, invitro cytotoxicity result of M. citrifolia EOs treated A549 lung cancer cells was clearly observed. The cytotoxicity result confirmed that the 500 µg/mL of M. citrifolia EOs against A549 lung cancer cells as fixed as IC₅₀ dose. Hence, current study conclude, M. citrifolia is the excellent medicinal plant to inactivate bacterial growth and cancer cells efficiently.

近年来，由于缺乏足够的药物，多重耐药菌（MDR）和肺癌细胞正在威胁着全世界人类。有人建议，新来源需要发现新品种的药物、抗生素和其他形式来根除这些感染。同样，本研究使用药用植物海巴戟( M. citrifolia ) 来抑制细菌感染和癌细胞。首先，LC-MS 测量清楚地报告了来自药用植物M. citrifolia的有效精油。它对奇异变形杆菌、大肠杆菌、铜绿假单胞菌和金黄色葡萄球菌具有优异的抗菌性能，琼脂井扩散抑制区分别为 24、22、26 和 18 个。随后，液体干扰测定在 1000 µg/mL 浓度下对所有测试的病原体表现出 97%、96%、94% 和 90% 的抑制。此外，M. citrifolia EOs具有优异的抗菌活性，与其他时间间隔相比，在1000 µg/mL浓度下24小时后完全抑制细菌生长。随后，通过共焦激光扫描电子显微镜有效地观察到细胞内膜和更多具有浓缩染色体样结构的死亡细胞。然后，清楚地观察到M. citrifolia EOs处理A549肺癌细胞的体外细胞毒性结果。细胞毒性结果证实500 µg/mL的柑橘EOs对A549肺癌细胞的作用与IC ₅₀剂量相同。因此，目前的研究得出结论，柑橘是一种能够有效灭活细菌生长和癌细胞的优秀药用植物。