Studies on the impact of hypertension (HTN) on the outcome of patients with atrial fibrillation (AF) in the Middle East are scarce. The aim of this contemporary multicenter study is to evaluate the effect of the coexisting HTN on the baseline clinical profiles and 1-year prognosis in a cohort of Middle Eastern patients with AF. Consecutive AF patients in 29 hospitals and cardiology clinics were enrolled in the Jordan AF study (May 2019-December 2020). Patients were prospectively followed up for 1 year, and the study had no influence on their treatment, which was at the discretion of the treating physician. We compared clinical features, use of medications, and 1-year prognosis in patients with AF/HTN compared with AF/no HTN. Among 1849 non-valvular AF patients, 76.4% had HTN, with higher prevalence of diabetes, dyslipidemia, coronary heart disease, stroke, and left ventricular hypertrophy in HTN patients. There was a higher thromboembolic and bleeding risk among HTN patients. At 1 year, HTN patients had significantly higher rates of stroke and systemic embolism (SSE) (4.5%), acute coronary syndrome (ACS) (2.4%), rehospitalization (27.9%), and major bleeding events (3.0%) compared with non-HTN patients. In this cohort, the coexistence of HTN was associated with worse baseline clinical profile and 1-year outcomes.

中文翻译：

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中东心房颤动和高血压患者的临床概况和一年结果：约旦心房颤动研究分析。

关于中东地区高血压 (HTN) 对心房颤动 (AF) 患者预后影响的研究很少。这项当代多中心研究的目的是评估共存的 HTN 对中东 AF 患者队列的基线临床特征和 1 年预后的影响。约旦 AF 研究（2019 年 5 月至 2020 年 12 月）连续招募了 29 家医院和心脏病诊所的 AF 患者。对患者进行了为期一年的前瞻性随访，该研究对他们的治疗没有影响，这由治疗医生自行决定。我们比较了 AF/HTN 患者与 AF/无 HTN 患者的临床特征、药物使用和 1 年预后。在1849名非瓣膜性房颤患者中，76.4%患有高血压，高血压患者糖尿病、血脂异常、冠心病、脑卒中和左心室肥厚的患病率较高。高血压患者的血栓栓塞和出血风险较高。1 年时，HTN 患者的中风和全身性栓塞 (SSE) (4.5%)、急性冠脉综合征 (ACS) (2.4%)、再住院 (27.9%) 和大出血事件 (3.0%) 的发生率显着高于对照组非高血压患者。在该队列中，HTN 的共存与较差的基线临床特征和 1 年结果相关。