Altered HCAR3 expression may underlying the blunted niacin responses of the psychiatric disorders and the risk of schizophrenia,Psychiatry and Clinical Neurosciences

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Altered HCAR3 expression may underlying the blunted niacin responses of the psychiatric disorders and the risk of schizophrenia
Psychiatry and Clinical Neurosciences ( IF 11.9 ) Pub Date : 2023-11-20 , DOI: 10.1111/pcn.13617
Jie Jiang ₁ , Dandan Wang ₁ , Yan Gao ₁ , Liya Sun ₂ , Shuhui Li ₁ , Xiaowen Hu ₁ , Zhuyun Li ₁ , Juan Zhang ₁ , Feng Ji ₃ , Yusheng Tian ₄ , Lili Guan ₅ , Zhiqiang Li _{1,

6} , Lin He ₁ , Chunling Wan _{1,

2}

Affiliation

Blunted niacin response (BNR) was an endophenotype of schizophrenia, but the underlying mechanism remains unclarified. The objective of this study was to verify whether genes associated with BNR pathway constitute the genetic basis and the pathological mechanism of BNR phenotypic psychiatric patients.

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