BACKGROUND Multimorbidity is a growing problem. The number and complexity of (non-)pharmaceutical treatments create a great burden for patients. Treatment burden refers to the perception of the weight of these treatments, and is associated with multimorbidity. Measurement of treatment burden is of great value for optimizing treatment and health-related outcomes. OBJECTIVE We aim to translate and validate the Multimorbidity Treatment Burden Questionnaire (MTBQ) for use in the Dutch population with multimorbidity and explore the level of treatment burden. METHODS Translating the MTBQ into Dutch included forward-backward translation, piloting, and cognitive interviewing (n = 8). Psychometric properties of the questionnaire were assessed in a cross-sectional study of patients with multimorbidity recruited from a panel in the Netherlands (n = 959). We examined item properties, dimensionality, internal consistency reliability, and construct validity. The level of treatment burden in the population was assessed. RESULTS The mean age among 959 participants with multimorbidity was 69.9 (17-96) years. Median global NL-MTBQ score was 3.85 (interquartile range 0-9.62), representing low treatment burden. Significant floor effects were found for all 13 items of the instrument. Factor analysis supported a single-factor structure. The NL-MTBQ had high internal consistency (α = 0.845), and provided good evidence on the construct validity of the scale. CONCLUSION The Dutch version of the 13-item MTBQ is a single-structured, valid, and compact patient-reported outcome measure to assess treatment burden in primary care patients with multimorbidity. It could identify patients experiencing high treatment burden, with great potential to enhance shared decision-making and offer additional support.

中文翻译：

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荷兰多重病患者治疗负担的测量：多重病治疗负担问卷（NL-MTBQ）的翻译和验证。

背景技术多重发病是一个日益严重的问题。（非）药物治疗的数量和复杂性给患者带来了巨大的负担。治疗负担是指对这些治疗的重量的感知，并且与多重发病率相关。治疗负担的测量对于优化治疗和健康相关结果具有重要价值。目的 我们的目标是翻译和验证多病治疗负担问卷 (MTBQ)，以供荷兰多病患者使用，并探讨治疗负担水平。方法 将 MTBQ 翻译成荷兰语包括前后翻译、试点和认知访谈 (n = 8)。问卷的心理测量特性在一项横断面研究中进行了评估，研究对象是从荷兰的一个小组中招募的患有多种疾病的患者（n = 959）。我们检查了项目属性、维度、内部一致性可靠性和构造有效性。评估了人群的治疗负担水平。结果 959 名患有多种疾病的参与者的平均年龄为 69.9 (17-96) 岁。全球 NL-MTBQ 评分中位数为 3.85（四分位数范围 0-9.62），治疗负担较低。该仪器的所有 13 个项目均发现了显着的地板效应。因子分析支持单因子结构。NL-MTBQ具有较高的内部一致性（α = 0.845），为量表的构建效度提供了良好的证据。结论 荷兰版本的 13 项 MTBQ 是一种结构单一、有效且紧凑的患者报告结果衡量标准，用于评估患有多种疾病的初级保健患者的治疗负担。它可以识别承受高治疗负担的患者，具有增强共同决策并提供额外支持的巨大潜力。