PURPOSE To review the neuro-ophthalmic manifestations of Lyme disease at a central Ohio pediatric tertiary care center. METHODS A retrospective chart review of patients diagnosed as having Lyme disease from September 2015 to September 2020 was completed. Demographic information, diagnosis dates, and manifestations of Lyme disease were recorded. Patients were excluded for age older than 18 years or lack of corroborated Lyme disease diagnosis. Descriptive statistics were performed. RESULTS Of the 212 cases of pediatric Lyme disease reviewed, 50 patients had neuroborreliosis. The data showed an increase in Lyme disease and neuroborreliosis cases from 2018 to 2020, with a preponderance of diagnoses in the summer months. Twenty-four patients had meningitis, and 6 of these patients (25%) were diagnosed as having bilateral optic disc edema that was clinically consistent with intracranial hypertension. CONCLUSIONS Papilledema in the setting of Lyme meningitis may be more common than previously reported in central Ohio. If Lyme disease meningitis is suspected, an opening pressure should be recorded at the time of lumbar puncture and, if elevated, an ophthalmologic evaluation for optic nerve edema is indicated. [J Pediatr Ophthalmol Strabismus. 20XX;X(X):XXX-XXX.].

中文翻译：

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小儿莱姆病神经眼科表现的每年发生率和季节性。

目的 回顾俄亥俄州中部儿科三级护理中心莱姆病的神经眼科表现。方法 对 2015 年 9 月至 2020 年 9 月诊断为莱姆病的患者进行了回顾性图表审查。记录人口统计信息、诊断日期和莱姆病的表现。患者因年龄超过 18 岁或缺乏确凿的莱姆病诊断而被排除。进行了描述性统计。结果 在审查的 212 例儿童莱姆病病例中，50 例患者患有神经疏螺旋体病。数据显示，从 2018 年到 2020 年，莱姆病和神经疏螺旋体病病例有所增加，其中夏季的诊断占多数。24 名患者患有脑膜炎，其中 6 名患者（25%）被诊断为双侧视盘水肿，临床上符合颅内高压。结论 莱姆脑膜炎患者的视乳头水肿可能比之前报道的俄亥俄州中部更为常见。如果怀疑莱姆病脑膜炎，应在腰椎穿刺时记录开放压，如果开放压升高，则需要进行眼科评估视神经水肿。[J 小儿眼科斜视。20XX;X(X):XXX-XXX.]。