We present a case of disulfiram-induced mania in a patient with both alcohol use disorder (AUD) and psychostimulant use disorder (PUD), without a history of psychosis or mania. This acute presentation may be linked to the increased dopamine levels caused by disulfiram metabolism. Our patient developed manic symptoms 10 days after starting disulfiram, prescribed to treat the AUD. It should be noted that the symptoms resolved rapidly after disulfiram cessation during hospitalization. Disulfiram use is an effective treatment for alcohol dependence. However, there are safety concerns associated with it and it requires close monitoring, particularly in patients with a history of mania, psychosis, or psychostimulant use.

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厌恶代理人：三思而后行。双硫仑所致躁狂一例报告

我们介绍了一例双硫仑引起的躁狂症患者，该患者同时患有酒精使用障碍（AUD）和精神兴奋剂使用障碍（PUD），但没有精神病或躁狂病史。这种急性表现可能与双硫仑代谢引起的多巴胺水平升高有关。我们的患者在开始治疗 AUD 的双硫仑 10 天后出现躁狂症状。值得注意的是，住院期间停用双硫仑后，症状很快消失。使用双硫仑是治疗酒精依赖的有效方法。然而，它存在相关的安全问题，需要密切监测，特别是对于有躁狂、精神病或精神兴奋剂使用史的患者。