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CRISPR/Cas9-based genome editing: A revolutionary approach for crop improvement and global food security
Physiological and Molecular Plant Pathology ( IF 2.7 ) Pub Date : 2023-11-29 , DOI: 10.1016/j.pmpp.2023.102191
Ghulam Muha-Ud-Din , Faizan Ali , Akhtar Hameed , Syed Atif Hasan Naqvi , Mir Muhammad Nizamani , Muhammad Jabran , Sohaib Sarfraz , Wang Yong

In the face of a growing global population, climate change, and limited arable land, the need for resilient, high-yielding crops is pressing. Traditional breeding methods have struggled to meet these demands, but CRISPR/Cas9-based genome editing offers a groundbreaking solution. This article provides an in-depth overview of CRISPR/Cas9's role in enhancing crop traits to ensure global food security. By harnessing modern sequencing technologies, researchers can precisely edit genes in crop plants especially major crops like Triticum aestivum, Oryza sativa, Zea mays, and Solanum tuberosum etc., imparting traits such as disease resistance and stress tolerance. The technology is pivotal to producing next-generation crops (NGC's) capable of adapting to changing climates and delivering higher yields and product quality. Ethical and regulatory considerations are important, but responsible governance of genome editing promises significant advancements in agriculture. This review highlights CRISPR/Cas9's transformative potential in crop improvement and its pivotal role in shaping the future of food production.



中文翻译:


基于 CRISPR/Cas9 的基因组编辑:作物改良和全球粮食安全的革命性方法



面对不断增长的全球人口、气候变化和有限的耕地,对抗灾高产作物的需求迫在眉睫。传统育种方法难以满足这些需求,但基于 CRISPR/Cas9 的基因组编辑提供了突破性的解决方案。本文深入概述了 CRISPR/Cas9 在增强作物性状以确保全球粮食安全方面的作用。通过利用现代测序技术,研究人员可以对农作物尤其是小麦、水稻、玉米、马铃薯等主要农作物的基因进行精确编辑,赋予其抗病、耐逆等性状。该技术对于生产能够适应气候变化并提供更高产量和产品质量的下一代作物(NGC)至关重要。伦理和监管方面的考虑很重要,但负责任的基因组编辑治理有望在农业领域取得重大进步。这篇综述强调了 CRISPR/Cas9 在作物改良方面的变革潜力及其在塑造粮食生产未来方面的关键作用。

更新日期:2023-11-29
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