Cutaneous melanoma can metastasize to almost any organ, including in-transit metastases, lymph nodes, liver, lungs, brain, and bones. Spread to the gastrointestinal tract is less common and generally concerns the small bowel, colon, and stomach. Gallbladder involvement is rarer, and only few cases describe it as the sole site of metastasis upon diagnosis. Melanoma metastases to the gallbladder are usually detected on staging or surveillance imaging, as patients usually show few or no symptoms. In resectable stage IV melanoma patients, complete surgical resection appears to improve the prognosis. However, due to the rarity of isolated gallbladder metastasis of melanoma, there are no guidelines regarding the optimal surgical approach (endoscopic or open cholecystectomy). Here, we report the case of isolated gallbladder melanoma metastasis found after laparoscopic cholecystectomy performed in a 46-year-old female patient with no known history of cancer presenting with acute cholecystitis symptoms. Six weeks after surgery, the patient developed trocar site recurrence. This case highlights the importance of a planned and open surgery for resectable melanoma metastases rather than a laparoscopic approach.

中文翻译：

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腹腔镜胆囊切除术治疗未怀疑的孤立性黑色素瘤胆囊转移后套管针部位复发：病例报告和文献综述。

皮肤黑色素瘤几乎可以转移到任何器官，包括途中转移、淋巴结、肝脏、肺、大脑和骨骼。扩散到胃肠道的情况较少见，通常涉及小肠、结肠和胃。胆囊受累较为罕见，只有少数病例在诊断时将其描述为唯一的转移部位。黑色素瘤转移到胆囊通常是通过分期或监测成像来检测的，因为患者通常很少或没有症状。在可切除的 IV 期黑色素瘤患者中，完全手术切除似乎可以改善预后。然而，由于黑色素瘤孤立性胆囊转移的罕见性，目前尚无关于最佳手术方法（内镜或开腹胆囊切除术）的指南。在此，我们报告一例无已知癌症病史且出现急性胆囊炎症状的 46 岁女性患者，在腹腔镜胆囊切除术后发现孤立性胆囊黑色素瘤转移病例。手术六周后，患者出现套管针部位复发。该病例强调了针对可切除黑色素瘤转移进行计划性开放手术而不是腹腔镜手术的重要性。