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Giant Mature Ovarian Cystic Teratoma in a Pediatric Patient: Case Report and Literature Review.
Case Reports in Oncology Pub Date : 2023-10-06 , DOI: 10.1159/000534141
Adolfo Eduardo Barragán-Curiel 1 , Carlos Murillo-Zepeda 2 , Karla Fernanda Castro-Perez 2 , Francisco Omar Alcalá-Aguirre 2 , Lilian Sabinne Diaz-Montoya 2 , Omar Alfonso Ruiz-Félix 1 , José Antonio Acevedo-Delgado 1 , Moyra Velasco-Preciado 3
Affiliation  

Mature cystic teratomas, also called dermoid cysts, are the most common germ-cell ovarian neoplasms in children. On average, ovarian dermoid cysts are slow-growing neoplasms with a mean size between 6.4 and 7.0 cm that enlarge at a rate of 1.8 mm/year; however, these can reach large dimensions. Giant ovarian tumors are defined as those having a maximum diameter equal to or more than 15 cm; these represent a therapeutic challenge as they increase the risk of wide wound size and surgical invasiveness. In this paper, we present a case of a 10-year-old Hispanic female that complained of abdominal pain, distension, and nausea. Physical examination revealed a mass on the left side of the abdomen and an axial computed tomography found a large pelvic tumor extending to the abdominal region. After a laparotomy approach, pathology evaluation confirmed the diagnosis of mature cystic teratoma. The patient recovered thoroughly and had no complications at a 6-month follow-up. We conducted a literature review including English and Spanish reports about giant ovarian teratomas; we retrieved 16 cases from 2003 to 2023. We concluded that giant ovarian tumors may be underreported, particularly in resource-limited areas where tumors might grow unrecognized, and that English-language bias might play a substantial role in literature reviews involving case reports and case series.

中文翻译:

儿科患者巨大成熟卵巢囊性畸胎瘤:病例报告和文献综述。

成熟囊性畸胎瘤,也称为皮样囊肿,是儿童中最常见的生殖细胞卵巢肿瘤。平均而言,卵巢皮样囊肿是生长缓慢的肿瘤,平均大小在 6.4 至 7.0 厘米之间,以每年 1.8 毫米的速度扩大;然而,它们可以达到很大的尺寸。巨大卵巢肿瘤定义为最大直径等于或大于15厘米的肿瘤;这些都是治疗上的挑战,因为它们增加了大伤口和手术侵袭性的风险。在本文中,我们介绍了一名 10 岁西班牙裔女性的病例,她主诉腹痛、腹胀和恶心。体检发现腹部左侧有一个肿块,轴向计算机断层扫描发现一个巨大的盆腔肿瘤延伸到腹部区域。经过剖腹手术后,病理学评估证实了成熟囊性畸胎瘤的诊断。6个月随访后,患者完全康复,未出现并发症。我们进行了文献综述,包括关于巨型卵巢畸胎瘤的英文和西班牙文报道;我们检索了 2003 年至 2023 年的 16 个病例。我们得出的结论是,巨大卵巢肿瘤可能被低估,特别是在肿瘤可能在无法识别的情况下生长的资源有限的地区,并且英语语言偏见可能在涉及病例报告和病例的文献综述中发挥重要作用系列。
更新日期:2023-10-06
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