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Lipopolysaccharide (LPS) stimulation of Pancreatic Ductal Adenocarcinoma (PDAC) and macrophages activates the NLRP3 inflammasome that influences the levels of pro-inflammatory cytokines in a co-culture model
Cancer Biology & Therapy ( IF 3.6 ) Pub Date : 2023-11-29 , DOI: 10.1080/15384047.2023.2284857
Hariss G Paremes Sivam 1 , Beek Yoke Chin 2 , Sook Yee Gan 3 , Jia Hao Ng 4 , Agnes Gwenhure 4 , Elaine Wan Ling Chan 2
Affiliation  

Modified macrophages, tumor-associated macrophages (TAMs), are key contributors to the survival, growth, and metastatic behavior of pancreatic ductal adenocarcinoma (PDAC) cells. Central to the rol...

中文翻译:

脂多糖 (LPS) 刺激胰腺导管腺癌 (PDAC) 和巨噬细胞会激活 NLRP3 炎症小体,从而影响共培养模型中促炎细胞因子的水平

修饰的巨噬细胞,即肿瘤相关巨噬细胞 (TAM),是胰腺导管腺癌细胞 (PDAC) 存活、生长和转移行为的关键因素。角色的中心...
更新日期:2023-11-29
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