To examine if the substitution of different screen time intervals with light physical activity (LPA), moderate to vigorous physical activity (MVPA) and sleep is associated with cardiovascular indicators and inflammatory markers in children. This is a cross-sectional study developed with 186 children aged between six and 11 years old from public schools in southern Brazil. CRF was measured with the 6-minute running and walking test, following the Brazil Sports Project procedures. The percentage of fat was evaluated through DXA. LPA and MVPA were measured using accelerometers. Sleep and screen time were assessed by questionnaires answered by parents. Leptin and C-reactive protein were measured by fasting blood collection. Systolic and diastolic blood pressure were determined through a digital sphygmomanometer. Isotemporal substitution models were used for statistical analysis. Replacing 1 h of screen time with MVPA was associated with lower BMI, systolic and diastolic blood pressure, fat percentage, leptin, and C-reactive protein. When screen time was substituted for sleep time, lower waist circumference was observed. Regarding the substitution of 1 h of screen time with LPA, significant values were found only for leptin. The replacement of screen time with physical activities of different intensities and sleep time was associated with benefits in cardiovascular indicators and inflammatory markers in childhood.

中文翻译：

---

用体力活动和睡眠时间取代屏幕时间：对巴西儿童心血管指标和炎症标志物的影响

研究用轻度体力活动 (LPA)、中度至剧烈体力活动 (MVPA) 和睡眠替代不同屏幕时间间隔是否与儿童心血管指标和炎症标志物相关。这是一项针对巴西南部公立学校 186 名 6 岁至 11 岁儿童进行的横断面研究。CRF 是按照巴西体育项目程序通过 6 分钟跑步和步行测试进行测量的。通过 DXA 评估脂肪百分比。LPA 和 MVPA 使用加速度计测量。通过家长回答的问卷来评估睡眠和屏幕时间。通过空腹采血测定瘦素和C反应蛋白。通过数字血压计测定收缩压和舒张压。使用等时替代模型进行统计分析。用 MVPA 代替 1 小时的屏幕时间与较低的 BMI、收缩压和舒张压、脂肪百分比、瘦素和 C 反应蛋白相关。当用屏幕时间代替睡眠时间时，观察到腰围较低。关于用 LPA 替代 1 小时的筛选时间，仅针对瘦素发现了显着值。用不同强度的体力活动和睡眠时间代替屏幕时间与儿童时期心血管指标和炎症标志物的益处相关。