Hypomanic personality traits are present in the general population and represent a risk factor for developing bipolar disorder. This personality style, notably its social component, is linked to difficulties in theory of mind (i.e., ability to infer mental states). Exploring the neural correlates of mental states’ inference in individuals with these personality traits can provide meaningful insights into the development of bipolar disorder. The aim of the present study was therefore to investigate the potential impact of hypomanic traits on brain activation and task-based connectivity strength during a dynamic theory of mind task in a nonclinical population. A total of 52 nonclinical participants were recruited, and hypomanic traits were assessed with the Hypomanic Personality Scale. The severity of hypomanic traits was positively associated with right middle and inferior frontal gyri activations (in high vs. low inference in nonemotional condition and emotion vs. no emotion in high inference, respectively). It was also associated with stronger connectivity between the salience network (i.e., bilateral putamen and pallidum) and bilateral superior temporal gyri (high inference in nonemotional condition), and between cerebellar and temporal areas (high inference in emotional condition). These changes may either reflect adaptations or differential processing, and further studies are therefore mandatory.

轻躁狂人格特征存在于普通人群中，是发展双相情感障碍的危险因素。这种人格风格，尤其是其社会成分，与心理理论（即推断心理状态的能力）方面的困难有关。探索具有这些人格特征的个体的心理状态推断的神经相关性可以为双相情感障碍的发展提供有意义的见解。因此，本研究的目的是调查非临床人群的动态心理理论任务期间，轻躁狂特征对大脑激活和基于任务的连接强度的潜在影响。总共招募了 52 名非临床参与者，并使用轻躁狂人格量表评估轻躁狂特征。轻躁狂特征的严重程度与右额中回和下额回激活呈正相关（分别在非情绪状态下的高推理与低推理中以及高推理中的情感与无情感中）。它还与显着网络（即双侧壳核和苍白球）和双侧颞上回（非情绪状态下的高推理）之间以及小脑和颞区（情绪状态下的高推理）之间更强的连接相关。这些变化可能反映了适应或差异化处理，因此必须进行进一步的研究。