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Fibrinogen-to-Albumin Ratio and Glucose Metabolic States in Patients With Coronary Heart Disease.
Angiology ( IF 2.8 ) Pub Date : 2023-11-08 , DOI: 10.1177/00033197231206235
Xu Wang 1 , Ruiying Guo 1 , Mengnan Huang 1 , Zhu Li 2 , Ziqin Lai 1 , Rongrong Yang 1 , Lin Li 1 , Shan Gao 1 , Chunquan Yu 1
Affiliation  

This study investigated the relationship between fibrinogen-to-albumin ratio (FAR) and glucose metabolic state in patients with coronary heart disease (CHD). A total of 52,062 patients were enrolled in this study. Patients were classified according to FAR tertiles (T1: FAR < 0.0073; T2: 0.0073 ≤ FAR ≤ 0.0886; T3: FAR ≥ 0.0887). Patients were also classified into the normal glucose regulation (NGR) and elevated blood glucose (EBG) groups. The relationship between FAR and EBG was analyzed using logistic regression, and the association was evaluated according to sex and age. Among the participants, 32,471 (62.4%) had EBG, which was positively associated with FAR (odds ratio [OR], 1.19; 95% confidence interval [CI] 1.15-1.23). The OR of the FAR for EBG in males was higher than that in females (1.25; 95% CI 1.18-1.33 vs 1.15; 95% CI 1.10-1.20). Moreover, the OR of FAR for EBG was greater in patients aged 60 or younger (OR: 1.25; 95% CI 1.18-1.33) than in the elderly patients (over 60 years of age) (OR: 1.15; 95% CI 1.10-1.20). The results indicated a significant relationship between FAR and EBG and this association was higher in males and middle-aged patients.

中文翻译:

冠心病患者的纤维蛋白原与白蛋白比率和葡萄糖代谢状态。

本研究调查了冠心病(CHD)患者纤维蛋白原与白蛋白比值(FAR)与葡萄糖代谢状态之间的关系。共有 52,062 名患者参加了这项研究。根据 FAR 三分位数对患者进行分类(T1:FAR < 0.0073;T2:0.0073 ≤ FAR ≤ 0.0886;T3:FAR ≥ 0.0887)。患者还被分为正常血糖调节(NGR)组和血糖升高(EBG)组。使用逻辑回归分析FAR和EBG之间的关系,并根据性别和年龄评估相关性。在参与者中,32,471 名 (62.4%) 患有 EBG,这与 FAR 呈正相关(比值比 [OR],1.19;95% 置信区间 [CI] 1.15-1.23)。男性 EBG 的 FAR 的 OR 高于女性(1.25;95% CI 1.18-1.33 vs 1.15;95% CI 1.10-1.20)。此外,60 岁或以下患者的 FAR 对 EBG 的 OR(OR:1.25;95% CI 1.18-1.33)高于老年患者(60 岁以上)(OR:1.15;95% CI 1.10- 1.20)。结果表明 FAR 和 EBG 之间存在显着相关性,并且这种相关性在男性和中年患者中更高。
更新日期:2023-11-08
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