当前位置: X-MOL 学术Cardiol. Rev. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Impact of Body Mass Index on Cardiac Arrest Outcomes: A Systematic Review and Meta-Analysis.
Cardiology in Review ( IF 2.1 ) Pub Date : 2023-11-30 , DOI: 10.1097/crd.0000000000000633
Wangmin Xie 1 , Jie Zhou , Huifei Zhou
Affiliation  

The influence of an individual's body mass index (BMI) on cardiac arrest outcomes remains uncertain. The aim of this study is to evaluate the impact of BMI categories (underweight, normal BMI, overweight, and obese) on mortality and neurological outcomes in patients experiencing cardiac arrest. We comprehensively searched standard electronic databases (PubMed, EMBASE, and Scopus) for relevant observational studies published in peer-reviewed journals written in English. We calculated pooled effect estimates using random-effects models and reported them as odds ratios (ORs) with 95% confidence intervals (CIs). We included 20 studies in our meta-analysis. Individuals with normal BMIs and those who were underweight had similar risks of in-hospital mortality (OR, 1.20; 95% CI, 0.90-1.60), mortality within 6 months of discharge (OR, 0.92; 95% CI, 0.59-1.42), mortality after the 1-year follow-up (OR, 2.42; 95% CI, 0.96-6.08), and odds of favorable neurological outcomes at hospital discharge (OR, 0.86; 95% CI, 0.53-1.39) and at the 6-month follow-up (OR, 0.73; 95% CI, 0.47-1.13). The risks of in-hospital mortality and mortality within 6 months of discharge in overweight and obese individuals were similar to those in individuals with normal BMIs. However, overweight (OR, 0.57; 95% CI, 0.35-0.92) and obese individuals (OR, 0.67; 95% CI, 0.51-0.89) had lower risks of mortality after their 1-year follow-ups. For overweight and obese subjects, the reduced risk of mortality after the 1 year of follow-up was noted only for those with in-hospital cardiac arrest and not for those with out-of-hospital cardiac arrest. The odds of favorable neurological outcomes in both overweight and obese individuals were similar to those with normal BMIs. BMI does not significantly impact short-term mortality or neurological outcomes. Overweight and obese individuals appear to have a lower risk of long-term mortality, but this differed by the place of arrest and needs to be confirmed by others.

中文翻译:

体重指数对心脏骤停结果的影响:系统评价和荟萃分析。

个人体重指数 (BMI) 对心脏骤停结果的影响仍不确定。本研究的目的是评估 BMI 类别(体重过轻、BMI 正常、超重和肥胖)对心脏骤停患者死亡率和神经系统结局的影响。我们全面检索了标准电子数据库(PubMed、EMBASE 和 Scopus),以查找发表在同行评审英文期刊上的相关观察性研究。我们使用随机效应模型计算了汇总效应估计值,并将其报告为优势比 (OR),置信区间 (CI) 为 95%。我们的荟萃分析中纳入了 20 项研究。BMI 正常的个体和体重过轻的个体的院内死亡风险(OR,1.20;95% CI,0.90-1.60)和出院 6 个月内死亡率风险相似(OR,0.92;95% CI,0.59-1.42) 、1 年随访后的死亡率(OR,2.42;95% CI,0.96-6.08),以及出院时神经学结果良好的几率(OR,0.86;95% CI,0.53-1.39)和 6 岁时一个月随访(OR,0.73;95% CI,0.47-1.13)。超重和肥胖个体的院内死亡风险和出院 6 个月内死亡风险与 BMI 正常个体相似。然而,超重(OR,0.57;95% CI,0.35-0.92)和肥胖个体(OR,0.67;95% CI,0.51-0.89)在一年随访后死亡风险较低。对于超重和肥胖受试者,一年随访后,只有院内心脏骤停患者的死亡风险有所降低,院外心脏骤停患者则没有。超重和肥胖个体获得良好神经系统结果的几率与体重指数正常的个体相似。BMI 不会显着影响短期死亡率或神经系统结果。超重和肥胖者的长期死亡风险似乎较低,但这因逮捕地点而异,需要得到其他人的证实。
更新日期:2023-11-30
down
wechat
bug