BRCA1-associated ataxia-telangiectasia-mutated activator-1 (BRAT1) is responsible for cell cycle surveillance and mitochondrial function. The implications of adult-onset BRAT1-variant and the resulting phenotypic neurocognitive and imaging features have not been previously described.

中文翻译：

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经典霍奇金淋巴瘤定向治疗加剧了 BRAT1 相关脑白质营养不良。

BRCA1 相关共济失调毛细血管扩张突变激活因子 1 (BRAT1) 负责细胞周期监视和线粒体功能。成人发病的 BRAT1 变异的影响以及由此产生的表型神经认知和成像特征此前尚未被描述过。