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A Concise Review on Magnetic Nanoparticles: Their Properties, Types, Synthetic Methods, and Current Trending Applications
Current Nanoscience ( IF 1.5 ) Pub Date : 2023-12-01 , DOI: 10.2174/0115734137271993231109174718
Meenakshi M. 1 , Bhaskar R. 2 , S.K. Ashok Kumar 2 , Selva Kumar R. 3
Affiliation  

: In recent years, there has been significant research on developing magnetic nanoparticles (MNPs) with multifunctional characteristics. This review focuses on the properties and various types of MNPs, methods of their synthesis, and biomedical, clinical, and other applications. These syntheses of MNPs were achieved by various methods, like precipitation, thermal, pyrolysis, vapor deposition, and sonochemical. MNPs are nano-sized materials with diameters ranging from 1 to 100 nm. The MNPs have been used for various applications in biomedical, cancer theranostic, imaging, drug delivery, biosensing, environment, and agriculture. MNPs have been extensively researched for molecular diagnosis, treatment, and therapeutic outcome monitoring in a range of illnesses. They are perfect for biological applications, including cancer therapy, thrombolysis, and molecular imaging, because of their nanoscale size, surface area, and absence of side effects. In particular, MNPs can be used to conjugate chemotherapeutic medicines (or) target ligands/proteins, making them beneficial for drug delivery. However, up until that time, some ongoing issues and developments in MNPs include toxicity and biocompatibility, targeting accuracy, regulation and safety, clinical translation, hyperthermia therapy, immunomodulatory effects, multifunctionality, and nanoparticle aggregation.

中文翻译:

磁性纳米粒子简述:其性质、类型、合成方法和当前趋势应用

:近年来,人们在开发具有多功能特性的磁性纳米颗粒(MNP)方面进行了大量研究。本综述重点介绍 MNP 的性质和各种类型、其合成方法以及生物医学、临床和其他应用。这些 MNP 的合成是通过多种方法实现的,如沉淀、热、热解、气相沉积和声化学。MNP 是直径范围为 1 至 100 nm 的纳米材料。MNP 已用于生物医学、癌症治疗诊断、成像、药物输送、生物传感、环境和农业等领域的各种应用。MNP 已被广泛研究用于一系列疾病的分子诊断、治疗和治疗结果监测。由于其纳米级尺寸、表面积和无副作用,它们非常适合生物应用,包括癌症治疗、溶栓和分子成像。特别是,MNP 可用于缀合化疗药物(或)靶标配体/蛋白质,使其有利于药物输送。然而,直到那时,MNP 的一些持续存在的问题和发展包括毒性和生物相容性、靶向准确性、监管和安全性、临床转化、热疗、免疫调节作用、多功能性和纳米颗粒聚集。
更新日期:2023-12-01
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