Introduction The abscopal effect (AE) is a phenomenon, in which radiotherapy exerts an antitumour effect on distant lesions outside the primary irradiated area. Although immune checkpoint inhibitors have been widely studied for their potential to enhance the AE and improve patient outcomes, findings in cases of head and neck cancers remain limited. Case Presentation We report the case of a 72-year-old man who experienced lung oligoprogression during nivolumab treatment for metastatic hypopharyngeal cancer. Stereotactic body radiotherapy (SBRT) was administered to one of the lung lesions, after which both irradiated and nonirradiated lesions regressed. Upon an 18-month follow-up period after SBRT, the patient showed no disease progression or toxicity, and continued receiving nivolumab therapy. Conclusion The intent behind presenting this case report was to contribute to the accumulation of evidence regarding the AE in cases of head and neck cancer.

中文翻译：

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纳武单抗立体定向放疗治疗头颈癌肺转移后的远隔效应：病例报告。

引言 远隔效应（AE）是放射治疗对原发照射区域以外的远处病灶产生抗肿瘤作用的现象。尽管免疫检查点抑制剂因其增强 AE 和改善患者预后的潜力而得到广泛研究，但在头颈癌病例中的研究结果仍然有限。病例介绍 我们报道了一名 72 岁男性的病例，他在纳武利尤单抗治疗转移性下咽癌期间出现了肺部寡进展。对其中一个肺部病灶进行立体定向放射治疗（SBRT），之后照射和未照射的病灶均消退。SBRT 后 18 个月的随访期中，患者没有表现出疾病进展或毒性，并继续接受纳武单抗治疗。结论 提交本病例报告的目的是帮助积累有关头颈癌病例 AE 的证据。