Bartholin gland carcinoma is an extremely rare disease. Information regarding treatment is scarce and there is no strict consensus on best practice. All studies reporting cases of Bartholin's gland cancer were screened and evaluated for inclusion. Baseline characteristics of studies were extracted. A total number of 290 manuscripts collected were available for the review process. Studies included in a previous systematic review were not duplicated. In total, details of 367 patients were collected, as follows: histological features, clinical presentation, treatment, recurrent rate, treatment of recurrence and outcome. About 35% of Bartholin gland carcinoma were squamous cell carcinoma. Almost 50% of patients presented with advanced stage. The therapeutic approach was mainly surgery, and in 61% of those women lymph node assessment was performed. Recurrence occurred in 21% of cases. Bartholin gland cancer remains a challenge for gynecologic oncologists. Guidelines, centralization to referral centers and standardized therapy are needed.

中文翻译：

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原发性和复发性前庭大腺癌的治疗：代表 MITO 罕见癌症小组进行的系统评价。

前庭大腺癌是一种极其罕见的疾病。有关治疗的信息很少，而且对于最佳实践也没有严格的共识。所有报告前庭大腺癌病例的研究均经过筛选和评估以纳入。提取研究的基线特征。总共收集了 290 篇稿件可供评审。之前的系统评价中包含的研究没有重复。总共收集了367例患者的详细信息，如下：组织学特征、临床表现、治疗、复发率、复发治疗和结果。约35%的前庭大腺癌为鳞状细胞癌。近50%的患者已处于晚期。治疗方法主要是手术，其中 61% 的女性进行了淋巴结评估。21%的病例出现复发。前庭大腺癌仍然是妇科肿瘤学家面临的挑战。需要指南、集中转诊中心和标准化治疗。