Autologous mesenchymal stem cells (MSCs) are ideal for tissue regeneration because of their ability to circumvent host rejection, but their procurement and processing present logistical and time-sensitive challenges. Allogeneic MSCs provide an alternative cell-based therapy capable of positively affecting all human organ systems, and can be readily available. Extensive research has been conducted in the treatment of autoimmune, degenerative, and inflammatory diseases with such stem cells, and has demonstrated predominantly safe outcomes with minimal complications. Nevertheless, continued clinical trials are necessary to ascertain optimal harvest and transplant techniques.

中文翻译：

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体内移植后的同种异体间充质干细胞：综述。

自体间充质干细胞 (MSC) 是组织再生的理想选择，因为它们能够规避宿主排斥，但它们的获取和加工面临着后勤和时间敏感的挑战。同种异体间充质干细胞提供了一种替代的基于细胞的疗法，能够对所有人体器官系统产生积极影响，并且很容易获得。人们在利用此类干细胞治疗自身免疫性疾病、退行性疾病和炎症性疾病方面进行了广泛的研究，并证明其结果基本上是安全的，并发症最少。然而，需要持续的临床试验来确定最佳的收获和移植技术。