Peri-implant mucositis (PIM) is a pathological precursor of peri-implantitis, but its pattern of conversion to peri-implantitis is unclear and complicated to diagnose clinically, while none of the available protocols yield complete disease resolution. The aim of this study was the evaluation of PIM responsiveness to standard anti-infective mechanical treatment (AIMT) at clinical and biomarker levels, and estimation of the diagnostic capacity of bone markers as surrogate endpoints and predictors.

中文翻译：

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标准治疗后种植体周围粘膜炎的缓解：一项前瞻性分口研究

种植体周围粘膜炎（PIM）是种植体周围炎的病理学先兆，但其转化为种植体周围炎的模式尚不清楚，临床诊断也很复杂，而且没有一种可用的方案能够完全解决疾病。本研究的目的是在临床和生物标志物水平上评估 PIM 对标准抗感染机械治疗 (AIMT) 的反应，并评估骨标志物作为替代终点和预测因子的诊断能力。