Filamentous plant pathogens, including fungi and oomycetes, cause some of the most devastating plant diseases. These organisms serve as ideal models for understanding the intricate molecular interplay between plants and the invading pathogens. Filamentous pathogens secrete effector proteins via haustoria, specialized structures for infection and nutrient uptake, to suppress the plant immune response and to reprogram plant metabolism. Recent advances in cell biology have provided crucial insights into the biogenesis of the extrahaustorial membrane and the redirection of host endomembrane trafficking toward this interface. Functional studies have shown that an increasing number of oomycete effectors accumulate at the perihaustorial interface to subvert plant focal immune responses, with a particular convergence on targets involved in host endomembrane trafficking. In this review, we summarize the diverse mechanisms of perihaustorial effectors from oomycetes and pinpoint pressing questions regarding their role in manipulating host defense and metabolism at the haustorial interface.

Copyright © 2024 The Author(s). This is an open access article distributed under the CC BY-NC-ND 4.0 International license.

丝状植物病原体，包括真菌和卵菌，会引起一些最具破坏性的植物病害。这些生物体是了解植物与入侵病原体之间复杂的分子相互作用的理想模型。丝状病原体通过吸器（用于感染和营养吸收的特殊结构）分泌效应蛋白，以抑制植物免疫反应并重新编程植物代谢。细胞生物学的最新进展为吸外膜的生物发生和宿主内膜运输向该界面的重定向提供了重要的见解。功能研究表明，越来越多的卵菌效应子在吸器周围界面积聚，破坏植物局灶性免疫反应，特别集中在参与宿主内膜运输的目标上。在这篇综述中，我们总结了卵菌吸器周围效应器的不同机制，并指出了它们在吸器界面操纵宿主防御和代谢中的作用的紧迫问题。

版权所有 © 2024 作者。这是一篇根据 CC BY-NC-ND 4.0 国际许可证分发的开放获取文章。