CONTEXT Exercise can decrease central adiposity, but the effect of exercise dose and the relationship between central adiposity and exercise-induced compensation is unclear. OBJECTIVE Test the effect of exercise dose on central adiposity change and the association between central adiposity and exercise-induced weight compensation. METHODS In this ancillary analysis of a 6-month randomized controlled trial, 170 participants with overweight or obesity (mean±SD BMI: 31.5±4.7 kg/m2) were randomized to a control group or exercise groups that reflected exercise recommendations for health (8 kcal/kg/week [KKW]) or weight loss and weight maintenance (20 KKW). Waist circumference was measured, and dual-energy X-ray absorptiometry assessed central adiposity. Predicted weight change was estimated and weight compensation (weight change minus predicted weight change) was calculated. RESULTS Between-group change in waist circumference (control: 0.0 cm [95% CI: -1.0,1.0], 8 KKW: -0.7 cm [95% CI: -1.7,0.4], 20 KKW: -1.3 cm [95% CI: -2.4, -0.2]) and visceral adipose tissue (VAT; control: -0.02 kg [95% CI: -0.07,0.04], 8 KKW: -0.01 kg [95% CI: -0.07,0.04], 20 KKW: -0.04 kg [95% CI: -0.10,0.02]) was similar (P≥0.23). Most exercisers (82.6%) compensated (predicted weight change lower than actual weight change). Exercisers who compensated exhibited a 2.5 cm (95% CI: 0.8,4.2) and 0.23 kg (95% CI: 0.14,0.31) increase in waist circumference and VAT, respectively, versus those who did not (P<0.01). Desire to eat predicted VAT change during exercise (β=0.21; P=0.03). CONCLUSIONS In the presence of significant weight compensation, exercise at doses recommended for health and weight loss and weight maintenance leads to negligible changes in central adiposity.

中文翻译：

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随机对照试验期间运动引起的中心性肥胖变化：运动剂量的影响及其与补偿的关系。

背景运动可以减少中枢性肥胖，但运动剂量的影响以及中枢性肥胖与运动引起的代偿之间的关系尚不清楚。目的 检验运动剂量对中心性肥胖变化的影响以及中心性肥胖与运动引起的体重补偿之间的关系。方法 在这项为期 6 个月的随机对照试验的辅助分析中，170 名超重或肥胖的参与者（平均±SD BMI：31.5±4.7 kg/m2）被随机分为对照组或反映健康运动建议的运动组（8 kcal/kg/周 [KKW]) 或减肥和体重维持 (20 KKW)。测量腰围，并用双能X射线吸收仪评估中心性肥胖。估计预测的重量变化并计算重量补偿（重量变化减去预测的重量变化）。结果 组间腰围变化（对照：0.0 cm [95% CI: -1.0,1.0]，8 KKW：-0.7 cm [95% CI：-1.7,0.4]，20 KKW：-1.3 cm [95% CI：-2.4，-0.2]）和内脏脂肪组织（VAT；对照：-0.02 kg [95% CI：-0.07,0.04]，8 KKW：-0.01 kg [95% CI：-0.07,0.04]，20 KKW：-0.04 kg [95% CI：-0.10,0.02]）相似（P≥0.23）。大多数锻炼者（82.6%）进行了补偿（预测体重变化低于实际体重变化）。与未进行代偿的锻炼者相比，进行代偿的锻炼者腰围和增值税分别增加了 2.5 厘米（95% CI：0.8,4.2）和 0.23 公斤（95% CI：0.14,0.31）（P<0.01）。运动期间进食欲望预测增值税变化（β=0.21；P=0.03）。结论 在存在显着体重补偿的情况下，按照健康、减肥和维持体重推荐剂量进行运动对中心性肥胖的影响可以忽略不计。