Introduction Radiation and intra-arterial cisplatin infusion chemotherapy (RADPLAT) for advanced maxillary sinus cancer has accumulated evidence as a treatment with fewer complications and better 5-year survival rates. In this study, we report a case in which pterygoid muscle necrosis occurred 6 months following RADPLAT treatment for maxillary sinus cancer. Case Presentation The 45-year-old woman had a long history of taking immunosuppressants against rheumatoid arthritis (RA) prior to treatment. Although achieving complete response (CR) to RADPLAT, the patient developed trismus (1 fingerbreadth or less) 6 months following treatment. Abscess formation and recurrence were suspected from the imaging findings; however, the biopsy with endoscopy indicated necrotic tissue. Currently, 18 months have passed without cancer recurrence. Although trismus temporarily improved with rehabilitation, the width of the mouth opening is currently a few millimeters, so the patient can only take liquid food. Conclusion Pterygoid muscle necrosis should be recognized as a new major complication.

中文翻译：

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放射和动脉内顺铂输注化疗 (RADPLAT) 引起的翼状肌坏死：病例报告。

简介 放射治疗和动脉内顺铂输注化疗 (RADPLAT) 治疗晚期上颌窦癌已积累了证据，作为一种并发症更少、5 年生存率更高的治疗方法。在这项研究中，我们报告了一个病例，其中 RADPLAT 治疗上颌窦癌后 6 个月发生翼状肌坏死。病例介绍 这位 45 岁的女性在治疗前长期服用免疫抑制剂来治疗类风湿性关节炎 (RA)。尽管对 RADPLAT 实现完全缓解 (CR)，但患者在治疗后 6 个月出现牙关紧闭（1 指宽度或更少）。从影像学结果怀疑脓肿形成和复发；然而，内窥镜活检显示坏死组织。目前，18个月过去了，癌症没有复发。虽然牙关紧闭经过康复暂时得到改善，但目前张口宽度只有几毫米，因此患者只能进食流质食物。结论 翼状肌坏死应被视为新的主要并发症。