Background

Soft contact lenses have been developed and licensed for reducing myopia progression. These lenses have different designs, such as extended depth of focus (EDOF) and dual focus (DF). In this prospective, double-masked, cross-over study, different lens designs were investigated to see whether these had impact on accommodative microfluctuations and eye movements during reading.

Methods

Participants were fitted with three lenses in a randomised order; a single vision (SV) design (Omafilcon A2; Proclear), a DF design (Omafilcon A2; MiSight), and an EDOF lens design (Etafilcon A; NaturalVue),. Accommodative microfluctuations were measured at 25 cm for at least 60s in each lens, using a Shin-Nippon SRW-5000 autorefractor adapted to continuously record accommodation at 22Hz. Eye movement data was collected with the Thomson Clinical Eye Tracker incorporating a Tobii Eye bar. Eye movements include fixations per row, fixations per minute, mean regressions per row, total number of regressions, and total rightward saccades. Accommodation data was analysed using power spectrum analysis. Differences between the lenses were compared using a related sample two-way Friedman test.

Results

Twenty-three participants (18–29 years) were recruited to take part. The average mean spherical error was −2.65D ± 1.42DS, with an average age of 23.4 ± 3.5 years. No significant difference for accommodative microfluctuations was found. Significant differences were found for fixations per row (P = 0.03), fixations per minute (P = 0.008), mean regressions per row (P = 0.002), and total number of regressions (P = 0.002), but not total rightward saccades (P = 0.10). Post-hoc analysis indicated the EDOF lens results were significantly different from the other lenses, with more regressive eye movements observed.

Conclusions

Regressive saccades appear to increase when wearing EDOF lens designs, which may impact visual comfort. Further studies in children, over a longer period of adaptation are necessary to assess the potential impact of this finding on daily reading activities in children.

中文翻译：

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近视管理隐形眼镜设计对阅读时调节性微波动和眼球运动的影响

背景

软性隐形眼镜已被开发并获得许可，用于减少近视加深。这些镜头具有不同的设计，例如扩展景深 (EDOF) 和双焦点 (DF)。在这项前瞻性、双盲、交叉研究中，研究了不同的镜片设计，看看它们是否对阅读过程中的调节性微波动和眼球运动产生影响。

方法

参与者按随机顺序安装了三个镜片；单光 (SV) 设计（Omafilcon A2；Proclear）、DF 设计（Omafilcon A2；MiSight）和 EDOF 镜片设计（Etafilcon A；NaturalVue）。使用能够以 22Hz 连续记录调节的 Shin-Nippon SRW-5000 自动验光仪，在 25 cm 处测量每个镜片的调节微波动至少 60 秒。使用装有 Tobii Eye bar 的 Thomson 临床眼动仪收集眼球运动数据。眼球运动包括每行注视次数、每分钟注视次数、每行平均回归次数、回归总数和向右扫视总数。使用功率谱分析来分析住宿数据。使用相关样本双向弗里德曼测试来比较镜片之间的差异。

结果

招募了 23 名参与者（18-29 岁）参加。平均球面误差为-2.65D±1.42DS，平均年龄为23.4±3.5岁。调节性微波动没有发现显着差异。每行注视次数 (P = 0.03)、每分钟注视次数 (P = 0.008)、每行平均回归次数 (P = 0.002) 和回归总数 (P = 0.002) 存在显着差异，但向右扫视总数不存在显着差异 ( P = 0.10）。事后分析表明，EDOF 镜片的结果与其他镜片显着不同，观察到更多的回归性眼球运动。

结论

佩戴 EDOF 镜片设计时，后退眼跳似乎会增加，这可能会影响视觉舒适度。有必要对儿童进行更长时间的适应研究，以评估这一发现对儿童日常阅读活动的潜在影响。