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Frontline Gastroenterology Pub Date : 2024-01-01 , DOI: 10.1136/flgastro-2023-102603
R Mark Beattie

Diverticular disease is common, affecting 70% of the western population by the age of 80. In this issue Williams and colleagues provide a comprehensive overview discussing pathophysiology, classification and management. The incidence is rapidly increasing in younger age groups. Complications include acute diverticulitis, abscess, bleeding and perforation—most complications occur during the primary episode. Chronic symptoms are common and present a significant healthcare burden. The pathophysiology is complex with diet a significant contributory factor—nicely summarised in figure 1. Disease can be asymptomatic or symptomatic and then uncomplicated or complicated with complicated diverticulitis further categorised by the Hinchey and modified Hinchey classifications (figure 2) which guide treatment. The authors discuss preventative and treatment strategies (figure 3) including diet, lifestyle, probiotics and antibiotics (not always indicated) with endoscopic clipping and surgical intervention indicated in a proportion of cases. The review is authoritative, practical and up to date and as such essential reading. (See page 50). Alcohol-related hepatitis is the most florid presentation of alcohol-related liver disease and carries a high short-term and long-term mortality rate. In this issue Shearer and colleagues …

中文翻译:

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憩室病很常见,影响 70% 到 80 岁的西方人口。在本期中,Williams 及其同事对病理生理学、分类和治疗进行了全面概述。在较年轻的年龄组中,发病率正在迅速增加。并发症包括急性憩室炎、脓肿、出血和穿孔——大多数并发症发生在初次发作期间。慢性症状很常见,并带来重大的医疗负担。病理生理学很复杂,饮食是一个重要的影响因素——图 1 很好地总结了这一点。疾病可以是无症状的,也可以是有症状的,然后是不复杂的,也可以是并发复杂性憩室炎,根据 Hinchey 和改良的 Hinchey 分类(图 2)进一步分类,指导治疗。作者讨论了预防和治疗策略(图 3),包括饮食、生活方式、益生菌和抗生素(并不总是指出),并在部分病例中指出了内镜夹闭和手术干预。该评论具有权威性、实用性和最新性,因此是必不可少的读物。(参见第 50 页)。酒精相关性肝炎是酒精相关性肝病中最华丽的表现,具有很高的短期和长期死亡率。在本期希勒和同事中……
更新日期:2023-12-07
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