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Apart and back again: Reestablished neuronal connections restore walking after paralysis
Cell Stem Cell ( IF 23.9 ) Pub Date : 2023-12-07 , DOI: 10.1016/j.stem.2023.11.003 Qi Lin Cao , Chrystine M. Gallegos , Yiyan Zheng
中文翻译:
分开又回来:重建的神经元连接恢复瘫痪后的行走能力
更新日期:2023-12-08
Cell Stem Cell ( IF 23.9 ) Pub Date : 2023-12-07 , DOI: 10.1016/j.stem.2023.11.003 Qi Lin Cao , Chrystine M. Gallegos , Yiyan Zheng
Despite significant strides promoting axon regeneration after spinal cord injury (SCI), meaningful functional recovery remains elusive. Using a combination of approaches, Squair et al.1 elegantly demonstrate that axons damaged after SCI must be reconnected with their natural targets to recover lost neurological functions.
中文翻译:
分开又回来:重建的神经元连接恢复瘫痪后的行走能力
尽管在促进脊髓损伤(SCI)后轴突再生方面取得了重大进展,但有意义的功能恢复仍然难以实现。Squair 等人结合使用多种方法。图 1优雅地证明了 SCI 后受损的轴突必须与其自然目标重新连接,以恢复失去的神经功能。